Publications by authors named "Violetta Caserta"
Article Synopsis
- A study examined cognitive function in 74 adult patients with beta-thalassaemia and 45 healthy controls, finding that patients had significantly lower Full-Scale Intelligence Quotient (FSIQ) scores compared to controls, even when adjusting for education levels.
- Non-transfusion-dependent patients showed a trend towards better cognitive performance than transfusion-dependent patients, yet both groups had similar cognitive profiles on specific tests.
- The study concluded that adults with beta-thalassaemia exhibit cognitive impairments and higher rates of psychological issues, which could lead to serious long-term socio-economic challenges.
Multi-factorial causes jeopardize brain integrity in β-thalassaemia. Intracranial parenchymal and vascular changes have been reported among young β-thalassaemia patients but conventional magnetic resonance imaging (MRI) findings are contradictory making early MRI and magnetic resonance angiography (MRA)/venography monitoring a matter of debate. This study prospectively investigated 75 neurologically asymptomatic β-thalassaemia patients (mean-age 35·2 ± 10·7 years; 52/75 transfusion-dependent; 41/75 splenectomised) using a 3T magnetic resonance scanner; clinical, laboratory and treatment data were also collected.
View Article and Find Full Text PDFA higher rate of patients suffering from inflammatory bowel diseases (IBD) are reported to experience the symptom of fatigue compared with general population. Fatigue can impair quality of life of IBD patients by limiting their daily functioning. However, this problem is poorly understood and addressed.
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