Publications by authors named "Violeta Mihailova"

Although it is clear that probiotics improve intestinal barrier function, little is known about the effects of probiotics on the aging intestine. We investigated effects of 10-week bacterial supplementation of WCFS1, BL23, or DSM20213 on gut barrier and immunity in 16-week-old accelerated aging mice, which have a median lifespan of ~20 weeks, and their wild-type littermates. The colonic barrier in mice was characterized by a thin (< 10 μm) mucus layer.

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Distal myopathies represent a heterogeneous group of inherited skeletal muscle disorders. One type of adult-onset, progressive autosomal-dominant distal myopathy, frequently associated with dysphagia and dysphonia (vocal cord and pharyngeal weakness with distal myopathy [VCPDM]), has been mapped to chromosome 5q31 in a North American pedigree. Here, we report the identification of a second large VCPDM family of Bulgarian descent and fine mapping of the critical interval.

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