Publications by authors named "Vinothini Prabhakaran"
Engineering three-dimensional bone macro-tissues by guided fusion of cell spheroids.
Front Endocrinol (Lausanne)
January 2024
Article Synopsis
- - The study focuses on enhancing scaffold-free tissue engineering by bioassembling differentiated rat osteoblast (dROb) spheroids to create larger, functional bone tissue equivalents.
- - Spheroids in various seeding densities were monitored for cell growth and mineralization, utilizing custom-designed pillar supports for bioassembly, allowing maturation into a macrotissue over time.
- - Results showed that spheroids fused into a macrotissue larger than 2.5 mm with evidence of osteogenic maturation, confirmed by changes in specific molecular markers related to bone formation.
The bioavailability and pharmacokinetic disposition of tiamulin in broiler chicken were investigated after administration through the crop, drinking water, and feed at 40 mg/kg body weight. Residues of tiamulin in tissues of broiler chicken were also assessed. Plasma and tissue concentrations of tiamulin were analyzed by reverse-phase high-performance liquid chromatography (HPLC) method.
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