Publications by authors named "Vinothini Gopal"

Focusing on the huge importance associated in developing functional materials, this research study describes the synthesis, characterization of morphology, bactericidal activity and cytotoxic effect of iron oxide nanoparticles (IONPs). IONPs have been successfully fabricated through thermal decomposition of a diiron(III) complex precursor. The morphology of the nanoparticle has been delineated with different spectroscopic and analytic methods.

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Biofilm-mediated multidrug resistance has turned into major challenge for the treatment of C. albicans infections. In the present study, actinomycetes (SS5) isolated from marine crustacean were investigated for their ability to inhibit C.

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Article Synopsis
  • - The study focused on the bio-functional properties of an exopolysaccharide (EPS) from the actinobacterial strain Streptomyces griseorubens GD5, which was successfully produced in higher amounts (9.50 g/L) by adjusting the media components.
  • - Various analytical techniques confirmed the presence of multiple functional groups and sugar components, identifying GD5EPS as a heteropolysaccharide with a complex structure and good thermal stability.
  • - Importantly, GD5EPS demonstrated potential health benefits, including antioxidant and emulsifying properties, suggesting it could serve as a beneficial food supplement.
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The auto-aggregating ability of a probiotic is a prerequisite for colonization and protection of the gastrointestinal tract, whereas co-aggregation provides a close interaction with pathogenic bacteria. Peptide pheromone mediated signaling has been studied in several systems. However, it has not yet been explored in prokaryotes, especially actinobacteria.

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The present study was undertaken to select exclusive indigenous actinobacterial probiont for broiler health improvement based on in vitro probiotic potentials. In total, 18 actinobacterial cultures isolated from chicken were screened for survivability (resistance to low pH, pepsin, bile and pancreatin), colonization (auto-aggregation, hydrophobicity and co-aggregation) and safety (antibiotic susceptibility and non-haemolytic activity). Ten cultures showed excellent viability at pH 2 and most of the acid-tolerant isolates exhibited resistance to pepsin (3 mg/mL), bile (0.

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