Publications by authors named "Vinod N Alluri"
Cancer chemotherapeutic agents as human teratogens.
Birth Defects Res A Clin Mol Teratol
August 2012
Article Synopsis
- Cancer is a leading cause of death for women of reproductive age, and while combining pregnancy and cancer is uncommon, treatment with chemotherapy can sometimes be necessary.
- A review of literature from 1951 to 2012 looked at the effects of antineoplastic agents on pregnancy, focusing on adverse pregnancy outcomes (APOs) like birth defects and miscarriages.
- The study found that the risk of APOs varied by trimester and type of chemotherapy, with first-trimester exposure posing the greatest risks, especially from alkylating agents and antimetabolites; further research is needed to assess long-term effects on both mothers and children.
Medium chain acyl coenzyme A dehydrogenase (MCAD) deficiency: the case for screening all newborns.
J Okla State Med Assoc
May 2002
Medium chain acyl coenzyme A dehydrogenase (MCAD) deficiency is the most common inborn error of fatty acid oxidation with a frequency of 1 in 12,000, an estimated four new cases in the state of Oklahoma each year. The first clinical manifestation is a hypoglycemic episode any time between the newborn period to adulthood. Largely due to failure of diagnosis, the first episode can be lethal, with a frequency of early mortality of 25%.
View Article and Find Full Text PDF