Publications by authors named "Vinita Vijay Batra"
Article Synopsis
- Adolescent onset idiopathic nephrotic syndrome (INS) shows higher occurrences of atypical features and non-minimal change disease in histopathology compared to other age groups.
- The study was conducted at a pediatric nephrology clinic in North India, evaluating 33 adolescents diagnosed with idiopathic nephrotic syndrome.
- Key findings included that 70% had steroid-resistant nephrotic syndrome, with symptoms like hematuria in 39%, hypertension in 36%, and acute kidney injury in 27%, while most biopsies revealed non-minimal change disease.
Background: Impaired endothelial function is the initial step in atherogenesis, which is largely responsible for ischaemic heart disease and thrombotic strokes decades later.
Methods: Fourty two children with first episode nephrotic syndrome (FENS) aged 1-16 years and 40 controls were enrolled. Soluble thrombomodulin (sTM), tissue plasminogen activator (t-PA), plasminogen activator inhibitor -1 (PAI-1) and von-willebrand factor (vWF) levels were measured in plasma in FENS, at 12 weeks of drug induced remission and in steroid resistant nephrotic syndrome (SRNS) patients at diagnosis.