Publications by authors named "Vinicius Rio Verde Melo-Muniz"

Article Synopsis
  • This study investigated chronic sclerosing sialadenitis (CSS) to explore its histopathological and immunohistochemical features, with a focus on IgG4-related disease (IgG4-RD).
  • Out of 17 cases examined, the majority showed inflammatory and fibrotic changes, with notable presence of CD3-positive T lymphocytes and stromal fibroblasts, but only three cases met IgG4-RD criteria.
  • The findings suggest that CSS in the submandibular gland is primarily a reactive condition rather than directly related to IgG4-RD, providing valuable insights into its characteristics and immunological profile.
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Objective: This study seeks to investigate immunohistochemical parameters that could distinguish non-aggressive Central giant cell granuloma (CGCG) from aggressive CGCG, two groups of lesions which differ in their clinical and radiographic features and prognosis.

Material And Methods: 12 cases of non-aggressive CGCG and 11 cases of aggressive CGCG were investigated and associated the immunohistochemical expression of macrophages (CD68 and CD163), blood vessels (CD34 and CD105), lymphatic vessels (D2-40) and regulator proteins (p63 and Ki-67). Clinical and radiographic features were also studied.

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Objective: This study investigated components of the Hedgehog (HH) signaling pathway (SHH, GLI1), cyclin D1, and smooth muscle actin (SMA) in central giant cell granulomas (CGCG). The relationship between these proteins and myofibroblasts was also studied.

Material And Methods: Twelve cases of non-aggressive CGCG and 11 cases of aggressive CGCG were studied using immunohistochemistry for SHH, GLI1, Cyclin D1, and SMA.

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Background: Ameloblastoma with adenoid features are characterized by the presence of duct-like structures formed from the parenchyma of the tumor. This study was conducted to report a series of eight ameloblastomas with adenoid features, highlighting their clinicopathological and immunohistochemical aspects.

Material And Methods: Out of 71 cases of ameloblastomas, this study classified 8 cases as ameloblastomas with adenoid features.

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