Publications by authors named "Vinicius Medeiros Momesso"
Nanocarriers for photodynamic-gene therapy.
Willian Max O S de Santana Amanda Koberstain Surur Vinícius Medeiros Momesso Pedro Monteiro Lopes Celso V Santilli
Photodiagnosis Photodyn Ther
September 2023
Article Synopsis
- * It focuses on the promising combination of gene therapy (GT) and photodynamic therapy (PDT) as innovative strategies for cancer treatment over the past decade.
- * The review highlights the role of nanocarriers (nonviral vectors) in improving the effectiveness of these therapies, covering nanomaterial design, their interaction with biological environments, and performance in laboratory and live studies.*
Background: Antimicrobial Photodynamic Therapy (aPDT) is a treatment based on the interaction between a photosensitizer (PS), oxygen and a light source, resulting in the production of reactive oxygen species (ROS). There are two main types of reactions that can be triggered by this interaction: type I reaction, which can result in the production of hydrogen peroxide, superoxide anion and hydroxyl radical, and type II reaction, which is the Photodynamic Reaction, which results in singlet oxygen production. Antioxidant enzymes (e.
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