Publications by authors named "Vinicius G Oliveira"

This work aims to carry out an analysis of the evolution of the civil defense protection policy in Brazil, as well as to present an overview of research related to public policies on natural disasters in the world. The research was developed by documentary analysis of Brazilian policies on the protection of civil defense and bibliometric analysis of the global data. The evolution of public policy on natural disasters in Brazil was divided into four different moments: a) military civil defense (1942-1946), b) disaster assistance policy (1967-1988), c) Civil Defense system in construction (1988-2005), and d) consolidation of the civil defense system (2005- to the present).

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Wild mammals, especially rodents, can participate in the life cycle of ; however, the impact of these parasite strains on the severity of schistosomiasis remains unclear. The aim of this study was to comparatively evaluate the parasitological and immunopathological alterations induced by an strain isolated from the wild rodent (HS strain) and a parasite strain isolated from a human (LE strain) in experimentally infected mice. Male BALB/c mice were subcutaneously infected with 50 cercariae/mouse of either the HS or the LE strain and were evaluated for 12 weeks.

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The severity of chronic schistosomiasis has been mainly associated with the intensity and extension of the inflammatory response induced by egg-secreted antigens in the host tissue, especially in the liver and intestine. During acute schistosomiasis, eosinophils account for approximately 50% of the cells that compose the liver granulomas; however, the role of this cell-type in the pathology of schistosomiasis remains controversial. In the current study, we compared the parasite burden and liver immunopathological changes during experimental schistosomiasis in wild-type (WT) BALB/c mice and BALB/c mice selectively deficient for the differentiation of eosinophils (ΔdblGATA).

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Helminth infection can reduce the severity of inflammatory bowel disease. However, the modulatory mechanisms elicited by helminth infection are not yet fully understood and vary depending on the experimental model. Herein we evaluated the effect of acute infection of BALB/c mice with Strongyloides venezuelensis on the clinical course of ulcerative colitis induced by Dextran Sulfate Sodium (DSS) treatment of these animals.

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Article Synopsis
  • Sida pilosa, a plant used in Africa for various ailments, was studied for its effectiveness against schistosomiasis mansoni, showing schistosomicidal, antioxidant, and anti-fibrotic properties.
  • Mice infected with S. mansoni treated with aqueous extract or n-butanol fraction of S. pilosa experienced reduced worm burden and liver damage, alongside improvements in various biochemical markers.
  • Both treatments lowered harmful enzyme levels and reversed the effects of infection on certain proteins; however, the n-butanol fraction was less effective than the aqueous extract in some areas.
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Salmonella spp. are widespread in nature; however, human infections occur mainly through ingestion of contaminated food, specially poultry and eggs. In Brazil, the Ministry of Agriculture (MAPA) oversees food production in general, with the goal of preventing transmission of pathogens through the food chain.

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