Publications by authors named "Vinh Trung Nguyen"
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
View Article and Find Full Text PDFLimited contribution of non-intensive chicken farming to ESBL-producing Escherichia coli colonization in humans in Vietnam: an epidemiological and genomic analysis.
J Antimicrob Chemother
March 2019
Objectives: To investigate the risk of colonization with ESBL-producing Escherichia coli (ESBL-Ec) in humans in Vietnam associated with non-intensive chicken farming.
Methods: Faecal samples from 204 randomly selected farmers and their chickens, and from 306 age- and sex-matched community-based individuals who did not raise poultry were collected. Antimicrobial usage in chickens and humans was assessed by medicine cabinet surveys.
To understand the dynamics behind the worldwide spread of the mcr-1 gene, we determined the population structure of Escherichia coli and of mobile genetic elements (MGEs) carrying the mcr-1 gene. After a systematic review of the literature we included 65 E. coli whole genome sequences (WGS), adding 6 recently sequenced travel related isolates, and 312 MLST profiles.
View Article and Find Full Text PDFArticle Synopsis
- The study investigated how common antimicrobial resistance is among E. coli found on chicken farms in southern Vietnam, linking this resistance to specific farming practices and antibiotic use.
- Data was collected from 208 farms, with E. coli isolated and tested for resistance to 11 antimicrobials. Findings showed high levels of resistance, particularly to gentamicin and ciprofloxacin, and specific farming practices exacerbated this issue.
- The results indicated that frequent antibiotic use on these farms contributes to significant resistance rates, highlighting potential risks for both environmental and human health.