An Interesting Case of Fatal Myasthenic Crisis Probably Induced by the COVID-19 Vaccine.

A myasthenic crisis is a severe, life-threatening exacerbation of myasthenia gravis that causes a rapid onset of muscle weakness and fatigue that may result in tetraparesis, dyspnea, respiratory insufficiency, aspiration, and death. Bulbar muscle functions are markedly affected resulting in depressed cough reflex, swallowing, and speech. Thus, mechanical ventilation, supportive feeding, and critical care are essential for the survival of patients in a myasthenic crisis.

Predominance of heart failure in the Heart of Soweto Study cohort: emerging challenges for urban African communities.

Background: There is a paucity of data to describe the clinical characteristics of heart failure (HF) in urban African communities in epidemiological transition.

Methods And Results: Chris Hani Baragwanath Hospital services the 1.1 million black African community of Soweto, South Africa.

Anaemia and renal function in heart failure due to idiopathic dilated cardiomyopathy.

Background: Anaemia and renal dysfunction are common in patients with heart failure (HF). Most studies involve western cohorts with ischaemic aetiology receiving treatment likely to impair renal function.

Aims: To investigate the frequency of anaemia and renal dysfunction and the relationship between the two within a cohort of 163 newly diagnosed Black African idiopathic cardiomyopathy patients prior to commencing HF treatments and compare those findings to those of western HF cohorts.