Publications by authors named "Vineeth S Dasari"
Objective: This study aims to investigate the micro-hemodynamic effects of strut malapposition in patient-specific stented coronary bifurcations.
Methods: Using the mapping-back technique, three-dimensional reconstructions of clinical post-stenting artery bifurcations with strut malapposition were accurately generated from optical coherence tomography scans of 9 patients. Computational fluid dynamics (CFD) simulations were then conducted with these models to examine the impact of strut malapposition on various fluid dynamic parameters, including flow patterns, vorticity, strain rates, viscosity, and wall shear stress (WSS).
Article Synopsis
- The study focuses on how the design of coronary stents and the blood flow conditions after they are placed impact the success of heart procedures and patient health.
- An innovative algorithm for accurately creating 3D models of stents using intravascular ultrasound and angiography has been developed, showing high precision in complex stent configurations.
- This method not only confirms its accuracy in silicone models but also proves useful in clinical settings for assessing blood flow dynamics, aiding in optimizing stenting techniques and stent innovations.
Article Synopsis
- Optical coherence tomography (OCT) is a crucial imaging technique for diagnosing coronary artery disease, but accurate segmentation of the lumen is challenging due to various image artifacts.
- The research introduces a rapid automatic segmentation method that leverages nonuniform rational B-spline to effectively outline the OCT lumen edges while minimizing noise.
- Tested on 3300 OCT frames from 10 patients, the method operates in just 0.17 seconds per frame and offers accurate lumen segmentation and vessel reconstruction, enhancing the evaluation of coronary artery morphology.