Publications by authors named "Vineeth Ca"
Natural 3D Extra Cellular Matrix mimicking stem cells seeded decellularized scaffolds as a platform for tendon regeneration.
J Biomed Mater Res B Appl Biomater
September 2023
Article Synopsis
- The Achilles tendon, the body's strongest tendon, is susceptible to injury due to limited blood supply, affecting athletes, laborers, and the elderly.
- This study explores a new treatment using a tissue-engineered tendon product made from decellularized tendon (DT), stem cells, and an extract from Tinospora cordifolia, which shows promise in promoting tissue regeneration.
- The research demonstrates that the DT construct is non-toxic and has strong regenerative potential, offering a cost-effective alternative for tendon repair, thereby benefiting various groups prone to tendon injuries.
Current treatment systems for tendon injuries are very few and do not ensure complete cure. This is a serious health concern for sports persons and the aged population. It is known that the nano- or microsized particles of natural products such as /cumin seed () has been used traditionally as a home remedy for the treatment of tendon injuries.
View Article and Find Full Text PDFMesenchymal Stem Cells Seeded Decellularized Tendon Scaffold for Tissue Engineering.
Curr Stem Cell Res Ther
October 2021
Tendon is a collagenous tissue to connect bone and muscle. Healing of damaged/injured tendon is the primary clinical challenge in musculoskeletal regeneration because they often react poorly to treatment. Tissue engineering (a triad strategy of scaffolds, cells and growth factors) may have the potential to improve the quality of tendon tissue healing under such impaired situations.
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