Publications by authors named "Vineel Kondiboyina"
Chondrocytes respond to mechanical stimuli by increasing their intracellular calcium concentration. The response depends on the cellular environment. Previous studies have investigated chondrocytes under slow strain rates or cells embedded in hydrogels, but the response of chondrocytes in their native environment under physiologically relevant cyclic loads and dynamic hydrostatic pressure has not been studied.
View Article and Find Full Text PDFMaterial properties in regenerating axolotl limbs using inverse finite element analysis.
J Mech Behav Biomed Mater
February 2024
Article Synopsis
- The study investigates how the mechanical properties of regenerating axolotl forelimbs change at different stages of limb regeneration, specifically focusing on the viscoelastic characteristics.
- Results show that both the instantaneous shear modulus and equilibrium shear modulus increase during regeneration, while the stress relaxation times decrease as the limb matures.
- The findings emphasize the importance of the changing mechanical environment on regenerating tissues, linking molecular processes to overall tissue behavior and mechanical signaling.
Purpose: Obesity during adolescence has multisystem health consequences. The objective of this work was to determine whether preadolescent overweight/obese children's bones respond to a 9-month physical activity intervention by increasing bone density similar to healthy weight children.
Methods: Participants included overweight/obese (BMI > 85%) and healthy weight (15% < BMI < 85%) preadolescents (8-9 yr old).