The impact of FMR1 gene mutations on human reproduction and development: a systematic review.

Purpose: This is a comprehensive review of the literature in this field attempting to put the FMR1 gene and its evaluation into context, both in general and for the reproductive health audience.

Methods: Online database search of publications with systematic review of all papers relevant to ovarian reserve and assisted reproduction was done.

Results: Relevant papers were identified and assessed, and an attempt was made to understand, rationalize and explain the divergent views in this field of study.