Development of the AL-O-A Score for Delirium Screening in Acute Internal Medicine: a Monocentric Prospective Study.

Background: Delirium occurs frequently in acute internal medicine wards and may worsen the patient's prognosis; it deserves a fast, systematic screening tool.

Objective: Develop a delirium screening score for inpatients admitted to acute internal medicine wards.

Design: A monocentric prospective study between November 2019 and January 2020.

[Management of related contact sport mTBI].

Sports and hobbies are important cause of accident and the incidence of reported traumatic brain injury is about 10 000 case/years in Switzerland. Hockey and handball are very high-risk contact sports. The term « mild traumatic brain injury » (mTBI) involves a patient with an initial Glasgow coma scale between 13 and 15.

Dissociable components of spatial neglect associated with frontal and parietal lesions.

Spatial neglect is a complex neuropsychological disorder, in which patients fail to detect and respond to contralesional stimuli. Recent studies suggest that these symptoms may reflect a combination of different component deficits, associated with different lesion substrates. Thus, damage to right lateral prefrontal and inferior parietal regions produce different degrees of left neglect on cancellation and line bisection tasks, respectively.

Neuroanatomy of hemispatial neglect and its functional components: a study using voxel-based lesion-symptom mapping.

Spatial neglect is a perplexing neuropsychological syndrome, in which patients fail to detect (and/or respond to) stimuli located contralaterally to their (most often right) hemispheric lesion. Neglect is characterized by a wide heterogeneity, and a role for multiple components has been suggested, but the exact nature of the critical components remains unclear. Moreover, many different lesion sites have been reported, leading to enduring controversies about the relative contribution of different cortical and/or subcortical brain regions.

Abnormal attentional modulation of retinotopic cortex in parietal patients with spatial neglect.

Brain regions beyond visual cortex are thought to be responsible for attention-related modulation of visual processing [1, 2], but most evidence is indirect. Here, we applied functional magnetic resonance imaging (fMRI), including retinotopic mapping of visual areas, to patients with focal right-parietal lesions and left spatial neglect [3, 4]. When attentional load at fixation was minimal, retinotopic areas in right visual cortex showed preserved responses to task-irrelevant checkerboards in the contralateral left hemifield, analogously to left visual cortex for right-hemifield checkerboards, indicating a "symmetric" pattern in both hemispheres with respect to contralateral stimulation under these conditions.