Publications by authors named "Vincent V Rogers"
A laboratory bench procedure was developed to efficiently extract naphthenic acids from bulk volumes of Athabasca oil sands tailings pond water (TPW) for use in mammalian oral toxicity testing. This solvent-based procedure involved low solvent losses and a good extraction yield with low levels of impurities. Importantly, labour-intensive centrifugation of source water to remove solids was avoided, allowing processing of much larger volumes of water compared with previous protocols.
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- Naphthenic acids, major pollutants from oil sands extraction, were tested for toxicity in rodents to understand their risks to terrestrial wildlife.
- Adult female and male Wistar rats received varying doses (3, 30, or 300 mg/kg) in acute tests, showing food consumption drops and liver damage, with high doses leading to significant health issues.
- In long-term (subchronic) tests with doses of 0.6, 6, or 60 mg/kg over 90 days, findings indicated the liver as a potential target organ, suggesting that while acute toxicity may be low, repeated exposure could have harmful health effects.