Publications by authors named "Vincent Sylvestre"
The use of high-frequency Transcranial Magnetic Stimulation (HF-rTMS) of the right dorsolateral prefrontal cortex (DLPFC) in treating Post-traumatic Stress Disorder (PTSD) is currently regarded as a level B intervention (probable effectiveness). HF-rTMS has attracted interest as a neuromodulation therapeutic method for PTSD. Prolonged exposure and reactivation therapy are also regarded as first-line treatments for PTSD.
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- Esketamine has been proven effective for treatment-resistant depression (TRD), but its high cost and limited knowledge on treatment duration highlight the need for better outcome predictions.* -
- A study with TRD patients receiving esketamine identified two response trajectories—responders and non-responders—while showing that initial depression scores can predict future treatment success with 80% accuracy.* -
- Although the findings are promising, the study's observational nature and lack of a placebo group mean more controlled experiments are needed to validate these predictions and improve treatment decisions.*