Hemodynamic changes during a deep inspiration maneuver predict fluid responsiveness in spontaneously breathing patients.

Objective: We hypothesized that the hemodynamic response to a deep inspiration maneuver (DIM) indicates fluid responsiveness in spontaneously breathing (SB) patients.

Design: Prospective study.

Setting: ICU of a general hospital.

High-dose intravenous immunoglobulins dramatically reverse systemic capillary leak syndrome.

Objective: The objective of this study was to report the dramatic improvement of patients with systemic capillary leak syndrome obtained with high-dose intravenous immunoglobulins.

Design: Systemic capillary leak syndrome is a rare and life-threatening disorder characterized by hypotension that can lead to shock, weight gain, hypoalbuminemia, and elevated hematocrit secondary to unexplained episodic capillary fluid extravasation into the interstitial space. Because its cause is unknown, systemic capillary leak syndrome treatment has remained largely supportive.