Publications by authors named "Vincent Ogweno"
Background: In sub-Saharan Africa, one-quarter of all pregnancies occur in adolescents. Children born to adolescent mothers have poorer physical and socio-cognitive development. One reason may be inadequate knowledge on childcare and psychosocial support during pregnancy and post partum, since adolescent mothers have less antenatal care attendance and overall interaction with the health care system.
View Article and Find Full Text PDFBackground: HIV may increase SARS-CoV-2 infection risk and COVID-19 severity generally, but data are limited about its impact on postpartum women and their infants. As such, we characterized SARS-CoV-2 infection among mother-infant pairs in Nairobi, Kenya.
Methods: We conducted a nested study of 62 HIV-uninfected and 64 healthy women living with HIV, as well as their HIV-exposed uninfected (N = 61) and HIV-unexposed (N = 64) infants, participating in a prospective cohort.
Article Synopsis
- A variety of ELISAs have been created to detect SARS-CoV-2 antibodies since the pandemic began, highlighting the need to evaluate their reliability across different populations.
- This study compares the Platelia Total Ab Assay (Bio-Rad) with the Mount Sinai spike IgG ELISA using plasma samples from a mother-infant group in Nairobi, finding a high agreement (92.7%) and strong correlation (R = 0.973) between the two assays.
- The results suggest that both assays provide similar seroprevalence estimates for the Kenyan population and are effective regardless of HIV exposure status, supporting the Platelia assay as a viable option for seroprevalence research in Kenya.