Publications by authors named "Vincent M Wu"

Cancer immunotherapy is a field that garners significant interest, fueled by the clinical success of immune checkpoint inhibitors. In contrast to conventional cancer therapies, immunotherapies leverage the host's immune system by enhancing innate and adaptive immunity to control cancer progression. Despite these exciting advances, only a subset of patients respond to these drugs, and immunotherapies frequently result in immune-related toxicity.

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Article Synopsis
  • - This study presents a new type of flexible electrode array designed for non-invasive monitoring of cervical nerve activity, using silver-silver chloride electrodes and a custom data acquisition system with real-time visualization.
  • - Preliminary tests showed that this electrode design provides a high signal-to-noise ratio for capturing cervical neural recordings, and it has been named Cervical Electroneurography (CEN).
  • - The research identified distinct firing patterns during stress tests on the autonomic nervous system, suggesting potential for future development of a portable CEN device for tracking autonomic regulation changes in both healthy individuals and patients with clinical conditions.
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Glaucoma, the leading cause of irreversible blindness, affects >70 million people worldwide. Lowering intraocular pressure via topical administration of eye drops is the most common first-line therapy for glaucoma. This treatment paradigm has notoriously high non-adherence rates: ranging from 30% to 80%.

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We developed an operationally simple electrolytic design for the surface treatment of short carbon fibers. Using X-ray photoelectron spectroscopy (XPS), we demonstrated that the electrochemical surface treatment of discontinuous fibers is highly reproducible, uniform, and tunable. Specifically, total amounts of surface oxygen and nitrogen contents (0 to 17 atomic %) as well as surface oxygen-to-nitrogen ratio (1:0 to 1:2) vary significantly over the ranges of each processing parameter: applied voltage (1.

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