Publications by authors named "Vincent Laudon"
Objective: To evaluate the gene and protein expression of nerve growth factor (NGF) and substance P (SP) in the bladder 8 weeks after diabetes induction and investigate the pathogenesis of diabetic cystopathy.
Methods: Thirty Wistar rats were divided into three groups: control (n = 10), streptozotocin-induced diabetic group (n = 10) and Pygeum africanum (P. africanum) group (n = 10; diabetic rats were given P.
Objective: To evaluate the effect of Pygeum africanum on oxidative stress and functional changes of the bladder after diabetes induction.
Materials And Methods: Thirty-two adult Wistar male rats were treated daily for 8 weeks and grouped as follows: Control group (n = 6), Streptozotocin-induced diabetic group (n = 10), diabetes plus P. africanum group (n = 10), and control plus P.
Objectives: To investigate the alterations of urine transforming growth factor-beta1 (TGF-beta1) and basic fibroblast growth factor (bFGF) following bladder outlet obstruction (BOO) in rats and to determine their correlation with the impaired detrusor contractibility.
Methods: Wistar rats were divided into control, 2-week BOO 6-week and BOO groups. Impaired detrusor contractibility was quantified by measuring detrusor contraction force (DCF) of detrusor strip stimulated by carbachol.
Objective: To investigate the clinical significance of E-cadherin (E-CD) expression in human bladder transitional cell carcinoma (TCC) tissue and soluble forms of E-cadherin (sE-CD) in the urine of patients with TCC.
Materials And Methods: One hundred and two specimens of bladder TCC and 10 normal bladder tissues were stained immunohistochemically with anti-E-CD monoclonal antibody. The urinary sE-CD from 59 subjects with TCC or controls was measured with enzyme-linked immunosorbent assay (ELISA).
Article Synopsis
- The study aimed to analyze the levels of hydroxyproline (Hyp) and the expression of two growth factors, TGF beta1 and bFGF, in the bladder of rats 8 weeks after diabetes was induced.
- Thirty Wistar rats were divided into three groups: a control group, a diabetic group, and a group receiving Tadenan treatment, with various methods employed to evaluate protein and mRNA expression in the bladder.
- Findings indicated that diabetic rats had increased hydroxyproline and higher levels of TGF beta1 and bFGF compared to controls, while Tadenan treatment significantly reduced these levels in diabetic rats.