In Vitro and In Silico Anthelmintic Activity of Extracts of and on .

The aim of this study was to assess the anthelmintic activity of and , on a nematode model, to promote their use in the Cameroonian pharmacopoeia for the treatment of helminthiases. One nematode was used, . First, the effect of the extracts on the eggs and larval stages (L1, L2, and L3) of was evaluated, 100 L of extract and 100 L of parasite suspension (containing 50 eggs) were mixed in a 96-well microplate.

Antimalarial Efficacy of Ethanol Extract of Bridelia micrantha Stem Bark against Plasmodium berghei-Infected Mice.

Background: The spread of drug resistance is a significant issue, particularly in endemic countries with limited resources. The aim of this study was to evaluate antimalarial and antioxidant activity of in order to justify its use in traditional medicine.

Methods: Evaluation of the antimalarial activity of was carried out according to the model of the suppressive and curative test of Peters' over 4 days in infected mice.

Uptake of intermittent preventive treatment of malaria in pregnancy and risk factors for maternal anaemia and low birthweight among HIV-negative mothers in Dschang, West region of Cameroon: a cross sectional study.

Background: Approximately 32 million pregnant women are at risk of malaria with up to 10,000 maternal deaths and 200,000 neonates at risk annually. Intermittent Preventive Treatment (IPT) with sulfadoxine-pyrimethamine (SP) is recommended by the World Health Organization (WHO) to reduce disease in pregnancy and adverse maternal and newborn outcomes. At least three doses of SP should be taken by pregnant women during antenatal consultation (ANC) beginning from the thirteenth week of pregnancy till parturition.

Efficacy of Stem Bark Ethanol Extract in the Treatment of Cerebral Malaria in Mice Using NK65 Strain.

Background: Cerebral malaria is one of the most severe and dangerous forms of malaria and is potentially fatal. This study was aimed at evaluating the anticerebral malaria efficacy of used by traditional healers.

Method: Fifty grams of stem bark was macerated in 1 L ethanol (95%) for 72 h.

Nematocidal Activity of Ethanol and Aqueous Extracts of Seeds against using the Worm Microtracker Method.

Background: Infections with gastrointestinal helminths constitute a serious obstacle to the good health of the local population in most African Countries. The aim of this study was to evaluate the anthelminthic activity of ethanol and aqueous extracts against using the worm microtracker.

Method: Aqueous and ethanolic extracts of were prepared.

Antimalarial Efficacy and Antioxidant Activity of Stem Bark Ethanol Extract Using Induced-Malaria in Mice.

Background: Malaria remains a major public health problem in the tropical and subtropical regions. This study aimed of investigating the antimalarial and antioxidant activities of ethanol extract of stem bark. .

Epidemiology of schistosomiasis in the town of Manjo, littoral - Region,Cameroon.

Background: Schistosomiasis is endemic in Cameroon and continues to cause serious public health problems, especially among populations in rural areas. This study aimed at determining the prevalence and risk factors of urinary and intestinal schistosomiasis in Manjo.

Method: A cross-sectional study was conducted in the city of Manjo in 2020.

Antimalarial and Antioxidant Activities of Ethanolic Stem Bark Extract of in Swiss Albino Mice Infected with .

Background: Reduction of oxidative stress during malaria infection is considered as being of great benefit so long as treatment and drug development approaches are concerned. This study had the aim of evaluating the antimalarial and antioxidant activities of the ethanolic extract of in Swiss albino mice infected with the NK65 strain.

Methods: the antiplasmodial activity of the plant ethanolic extract was tested in a four-day suppressive and curative assay using in Swiss albino mice.

Antiplasmodial, Antioxidant, and Cytotoxic Activity of a Cameroonian Medicinal Plant Used for the Treatment of Malaria.

Introduction: Resistance to common antimalarial drugs and persistence of the endemicity of malaria constitute a major public health problem in Cameroon. The aim of this study was to evaluate the antiplasmodial, antioxidant, and cytotoxic activities of aqueous and ethanol extracts of used by Cameroonian traditional healers for the treatment of malaria.

Methods: Aqueous and ethanolic stem bark extracts were prepared according to standard procedures.

Antiplasmodial, Antioxidant and Cytotoxicity Activity of Ethanol and Aqueous Extracts of Stem Bark.

Background: Malaria is a serious public health problem, especially in sub-Saharan Africa. The aim of this study was to scientifically provide baseline information on the use of stem bark as an antimalaria drug by traditional healers.

Method: The stem barks of were harvested and dried to obtain powder, and fifty grams of the powder were soaked in ethanol and hot distilled water respectively, for the preparation of ethanol and aqueous extracts, then dried in an oven at 40°C for the ethanol extract and 50°C for the aqueous extract.

Antiplasmodial, Cytotoxicity, and Antioxidant Activities of (Ochnaceae): A Cameroonian Plant Commonly Used to Treat Malaria.

Background: Malaria is the leading cause of morbidity and mortality in African countries. We aimed this study at evaluating the antiplasmodial, antioxidant, and cytotoxicity activity of extracts.

Method: The aqueous and ethanol extracts were obtained by maceration.

Antihelminthic Activity of on Using an Automated High-Throughput Method.

Background: There are about 13 parasitic infections that are responsible for significant morbidity and mortality but have not received the attention they deserve; thus, they are now known as "neglected tropical diseases" (NTDs). This study was aimed at evaluating the antihelminthic activities of using an automated high-throughput method.

Methods: The antihelminthic activity effect of the extracts against .

Trends of potential waterborne diseases at different health facilities in Bamboutos Division, West Region, Cameroon: a retrospective appraisal of routine data from 2013 to 2017.

Many Cameroonian cities lack access to potable drinking water where populations rely on alternative water sources of doubtful quality. This study aimed at describing the trends and patterns of waterborne diseases (WBDs) reported in some health facilities in Bamboutos Division between 2013 and 2017 as baseline data towards understanding the profile of WBDs in this area. A retrospective review of clinical data kept on patients who visited the main health facilities in Bamboutos Division from January 2013 to December 2017 was conducted.

Malaria and Helminth Coinfection among Children at the Douala Gyneco-Obstetric and Pediatric Hospital.

Background: Malaria and helminth infections are major public health issues in sub-Saharan Africa including Cameroon. This study was aimed at determining the prevalence and risk factors associated with malaria and helminth coinfection among children in the Douala Gyneco-Obstetric and Pediatric Hospital (HGOPED) in Douala, southwestern Cameroon. .

Diversity of tsetse flies and trypanosome species circulating in the area of Lake Iro in southeastern Chad.

Background: African trypanosomiases are vector-borne diseases that affect humans and livestock in sub-Saharan Africa. Although data have been collected on tsetse fauna as well as trypanosome infections in tsetse flies and mammals in foci of sleeping sickness in Chad, the situation of tsetse fly-transmitted trypanosomes remains unknown in several tsetse-infested areas of Chad. This study was designed to fill this epidemiological knowledge gap by determining the tsetse fauna as well as the trypanosomes infecting tsetse flies in the area of Lake Iro in southeastern Chad.

Intestinal Helminth Infections and Associated Risk Factors among School-Aged Children of Bamendjou Community, West Region of Cameroon.

Background: Infection with intestinal nematodes is of major public health concern worldwide, and school-age children and pregnant women are the principal victims. The present study was undertaken to provide baseline information on the status of gastrointestinal nematodes among school-age children in Bamendjou. .

Gastrointestinal Nematodes among Residents in Melong, Moungo Division, Littoral Region, Cameroon.

Background: Intestinal parasitic infections are among the most common infections worldwide. The present study was undertaken to provide baseline information on the status of gastrointestinal nematodes in Melong Subdivision, Moungo Division, Littoral Region, Cameroon. .

Risk Factors Associated with Prevalence of , , and among Women at the District Hospital of Dschang, West Region, Cameroon.

Background: Vaginal or genitourinary infections are a major cause of morbidity, sterility, and increase in the vulnerability to cancers and HIV/AIDS infection. The aim of this study was to determine the prevalence of vaginal infections of , , and among women in the locality of Dschang, West Region of Cameroon.

Method: A prospective study was carried out in the District Hospital of Dschang.

Effect of Impregnated Mosquito Bed Nets on the Prevalence of Malaria among Pregnant Women in Foumban Subdivision, West Region of Cameroon.

Background: Malaria is one of the major public health problems in many tropical developing countries including Cameroon. Impregnated mosquito bed nets are one of the control measures put in place by the WHO and adopted by the Cameroon's Ministry of Public Health to fight against malaria in pregnancy. This study was a population-based cross-sectional study that investigated the level of adherence, respondent's knowledge, altitude, and practices toward malaria prevention and control.

Inventory and taxonomy of phlebotomine sand flies of the Mokolo leishmaniasis focus, northern Cameroon, with description of new Sergentomyia taxa (Diptera: Psychodidae).

Leishmaniasis is endemic in northern Cameroon. However, the sand fly vectors have not been incriminated. A sand fly species inventory was generated by integrating a number of techniques.

First detection of Leishmania donovani in sand flies from Cameroon and its epidemiological implications.

Objectives: A sound knowledge of the vector-host-parasite transmission dynamics is a prerequisite for adequate control measures of vector-borne diseases. To achieve this, an entomological investigation was conducted in the cutaneous leishmaniasis (CL) endemic focus of Mokolo District, northern Cameroon to identify the insect vector(s) of the disease.

Methods: Phlebotomine sand flies were collected in and around Mokolo using New Standard CDC Miniature Light Traps.

Preliminary study of ectoparasites of horses in the western highlands of Cameroon.

To evaluate the prevalence of infestation of ectoparasites of horses, a total of 894 horses (367 males and 527 females), aged 1-7 years old were examined. Horses were groomed for collection of ectoparasites. Out of the horses examined, 164 came from Fundong, 80 from Acha, 30 from Fongo-Tongo, 30 from Fokoue and 17 from Dschang, all of which were infested with ectoparasites.

Evaluation of In Vivo Acaricidal Effect of Soap Containing Essential Oil of Chenopodium ambrosioides Leaves on Rhipicephalus lunulatus in the Western Highland of Cameroon.

A study on the acaricidal properties of foam soap containing the essential oil of Chenopodium ambrosioides leaves was carried out on Rhipicephalus lunulatus. Four doses (0.03, 0.

Knowledge and practice of family planning in Dschang municipality, Cameroon.

This study was conducted to examine factors which influence contraception in order to ameliorate services. For 12 consecutive months, 706 consenting women on fertility control presenting at the Dschang District Hospital, Cameroon were interviewed and cervical/blood samples collected for analysis. Study respondents were aged 15-50 years (mean 33.