Validation of a method for arsenic speciation in food by ion chromatography-inductively coupled plasma/mass spectrometry after ultrasonic-assisted enzymatic extraction.

A fully validated and rapid quantitative method is presented for determination of inorganic arsenic [arsenite, As(III) and arsenate, As(V)] and organic arsenic species (methylarsonic acid, dimethylarsinic acid, and arsenobetaine) by ion chromatography paired with inductively coupled plasma/MS after ultrasonic-assisted enzymatic extraction (UAEE) in rice- and seafood-based raw materials and finished products. This method gives toxicological meaning to arsenic analysis, since the sum of the toxic chemical forms As(III) and As(V) can be determined. In contrast to classical water-methanol extraction, UAEE enables drastic acceleration of sample extraction (5 min instead of several hours), while total arsenic extraction efficiency is improved without species conversion.

Determination of seven arsenic species in seafood by ion exchange chromatography coupled to inductively coupled plasma-mass spectrometry following microwave assisted extraction: method validation and occurrence data.

The determination of seven arsenic species in seafood was performed using ion exchange chromatography on an IonPac AS7 column with inductively coupled plasma mass spectrometry detection after microwave assisted extraction. The effect of five parameters on arsenic extraction recoveries was evaluated in certified reference materials. The recoveries of total arsenic and of arsenic species with the two best extraction media (100% H(2)O and 80% aqueous MeOH) were generally similar in the five seafood certified reference materials considered.

Optimisation and critical evaluation of a collision cell technology ICP-MS system for the determination of arsenic in foodstuffs of animal origin.

The determination of arsenic (75As) was studied using an ICP-MS equipped with collision cell technology (CCT). Different mixtures of gases (He and H2) were tested using HCl conditions and a He flow rate of 4 mL min(-1) was found to be suitable for the removal of the poly-atomic spectral interference [40Ar35Cl]+. Trueness of the optimised method has been evaluated in both standard and CCT modes on six certified reference materials in foodstuffs of animal origin and on three external proficiency testing schemes (FAPAS).

Simultaneous analysis of cadmium, lead, mercury, and arsenic content in foodstuffs of animal origin by inductively coupled plasma/mass spectrometry after closed vessel microwave digestion: method validation.

A method validation of the total analysis of cadmium (Cd), lead (Pb), arsenic (As), and mercury (Hg) in foodstuffs by inductively coupled plasma/mass spectrometry (ICP/MS) after closed vessel microwave digestion is presented. Due to the lack of reference method for ICP/MS techniques in food and, based on the project of the European Committee of Normalization (CEN/TC 275/WG 10), the Agence Française de Normalisation (AFNOR) guidelines NF V03-110 were used for the evaluation of this method based on 2 steps, sample preparation and multielement detection. Several criteria considered as compulsory (linearity, specificity, precision under repeatability conditions, and trueness) have been estimated and discussed, in addition to intermediate precision reproducibility, the limit of detection, and the limit of quantification.