Demonstration of a new resonance peak by proton NMR in rat pancreas stimulated with caerulein.

Low-resolution proton nuclear magnetic resonance (1H NMR) analysis of the pancreas of rats stimulated with caerulein, a cholecystokinin analog, was found to differ from that of control rats either fed ad libitum or fasted for two days. The hormonal stimulation induced (a) an increase in the longitudinal relaxation time T1; (b) a 1H NMR peak situated at 1.8 +/- 0.

Enhanced membrane phospholipid metabolism in human pancreatic adenocarcinoma cell lines detected by low-resolution 1H nuclear magnetic resonance spectroscopy.

The low-resolution proton nuclear magnetic resonance (NMR) spectra of human pancreatic adenocarcinomas maintained in nude mice and in culture exhibit characteristic features. First, the high values of longitudinal (T1) and transverse (T2) relaxation times were attributed to disturbances in the exchange of ions and water molecules in cancerous cells. Second, a new peak situated at about 1.