Publications by authors named "Vinay Venkatesh Varada"

Article Synopsis
  • The study evaluated the effects of CRD7 on performance and gut health in Swiss albino mice, showing that both non-encapsulated and electrohydrodyanamically encapsulated CRD7 increased body weight and feed intake over four weeks.
  • Supplementation with CRD7 enhanced gut barrier functions by increasing tight junction proteins, reducing inflammation, and promoting beneficial short-chain fatty acids, while causing no adverse effects in liver and intestinal tissues.
  • The encapsulated form of CRD7 effectively improved gut microbiota by increasing beneficial bacteria and reducing harmful ones, suggesting its potential use in food and feed formulations to support gut health and address related diseases.
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The current study aimed to validate the safety of electrohydrodynamically encapsulated CRD7 and CRD11 in accordance with guidelines of FAO/WHO and ICMR/DBT. assays such as mucin degradation, hemolysis of blood cells, antimicrobial susceptibility pattern, possession of virulence factors, biogenic amine, and ammonia production were assessed. In results, the cross-streak and co-culture techniques revealed that CRD7 and CRD11 were compatible Upon visual inspection through scanning electron and fluorescence microscopy, the integrity of bacterial cell membrane was confirmed even after the encapsulation process.

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In this study, 105 bacterial colonies were isolated from the feces of newborn healthy Bos indicus calves and 37 isolates were confirmed using morphological, biochemical tests, and genus-specific PCR as lactobacilli. 11 isolates were then short-listed for in vitro probiotic testing based on their ability to dwell under acid and bile stress. Species-level identification using 16S rRNA gene sequencing revealed that they were Ligilactobacillus salivarius.

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The current study is aimed to evaluate the effect of host-specific probiotics on the gut microbiome, performance, and select fecal biomarkers of gut health in preruminant buffalo calves. Eight Murrah buffalo calves (3-5 days old; 32.52 ± 0.

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Probiotics are living microorganisms that confer health benefits to host when administered in adequate amounts. To develop novel host-specific probiotic for their application as feed additive, the present study was undertaken to isolate and characterize probiotic strains of indigenous cattle-calves origin. A total of 55 colonies were isolated from 12 healthy calves, with 34 of the isolates being Gram-positive, catalase-negative and vancomycin-resistant.

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Probiotics have emerged as biotherapeutic adjuncts to combat neonatal calf gastrointestinal disorders. Therefore, they are considered a suitable alternative to antibiotics for maintaining a healthy and balanced gut microbiota. Hence, the current investigation was carried out to evaluate the effect of autochthonous probiotics on Murrah buffalo calves.

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