Treatment Modalities and Clinical Outcomes in Ocular Sequelae of Stevens-Johnson Syndrome Over 25 Years--A Paradigm Shift.

Purpose: To highlight and compare the outcomes of management for the ocular sequelae of Stevens-Johnson syndrome (SJS) over 25 years in a tertiary eye care institute.

Methods: A retrospective chart review of 798 eyes of 399 patients with SJS evaluated between January 1990 and December 2004 (group I) and of 847 eyes of 517 patients between January 2005 and December 2014 (group II) was done. The primary and secondary outcome measures were a change in the best-corrected visual acuity (BCVA) and an improvement in the symptoms and the ocular surface status, respectively.

Mucosal complications of modified osteo-odonto keratoprosthesis in chronic Stevens-Johnson syndrome.

Purpose: To describe clinical outcomes of complications afflicting the autologous oral mucous membrane graft after modified osteo-odonto keratoprosthesis surgery in chronic Stevens-Johnson syndrome (SJS).

Design: Prospective case series.

Methods: This study included 30 eyes of 30 patients with SJS-induced dry keratinized ocular surfaces; the patients underwent various stages of this procedure between August 2009 and February 2012.

Modified osteo-odonto keratoprosthesis--the Indian experience--results of the first 50 cases.

Purpose: To study the results of the modified osteo-odonto keratoprosthesis (MOOKP) surgery in bilateral end-stage ocular surface disorders.

Methods: The MOOKP surgery is performed as a routine in 3 stages. Stage 1A involves removal of the iris and anterior vitrectomy with a corneal transplant if indicated.

Mucous membrane grafting for lid margin keratinization in Stevens–Johnson syndrome: results.

Purpose: To study the efficacy of mucous membrane grafting asa surgical technique to address lid margin keratinization, an important cause for chronic blink-related microtrauma in Stevens–Johnson syndrome (SJS).

Methods: The keratinized strip of conjunctiva along the lid margin was excised and replaced by lip mucous membrane using fibrin glue in 54 eyes of 31 patients with lid margin keratinization after SJS. This was a retrospective case series carried out between April 2005 and November 2006.

Vitreoretinal surgery in eyes with Pintucci biointegrable keratoprosthesis.

Purpose: The purpose of this study was to describe the challenges in preoperative evaluation, complexity of surgical maneuvers, and intricacies of postoperative management in eyes with Pintucci biointegrable keratoprosthesis requiring vitreoretinal intervention. Ocular surface disorders like Stevens-Johnson syndrome, chemical burns, and ocular cicatrical pemphigoid render the eye inamenable to penetrating keratoplasty. Hence, permanent keratoprosthesis is used for visual rehabilitation in such eyes.