Publications by authors named "Vinay S Mallikarjuna"
Background: Extramedullary hematopoiesis (EMH) is usually seen in the reticuloendothelial system such as the spleen and liver; however, there have been rare case reports when EMH is seen in serous fluids (SFs). The aim of this study included analyzing the cytomorphological features of EMH in SFs in correlation with various clinicopathologic parameters and recognizing potential diagnostic pitfalls as well as their prognostic significance.
Methods: Clinicopathologic parameters and radiologic and pathologic information from the patients with a cytologic diagnosis of EMH were evaluated with cytology slides.
Article Synopsis
- * A study analyzed 21 cases of CGCG at Temple University Hospital from 2015 to 2022, focusing on patient demographics, symptoms, and diagnostic methods such as X-ray imaging and histological examination using H&E staining.
- * Findings revealed that the majority of cases affected the mandible (81%), many were asymptomatic (62%), and symptomatic cases commonly exhibited pain and fullness; differential diagnoses included brown
SHP1, a tyrosine phosphatase, negatively regulates B-cell receptor (BCR) signaling. Ibrutinib selectively inhibits BTK and has been approved for the treatment of several types of B-cell lymphomas, but not yet in diffuse large B-cell lymphoma (DLBCL). A phase 3 clinical trial of ibrutinib-containing regimen has been completed to evaluate its activity in subtypes or subsets of DLBCL patients.
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