Publications by authors named "Vinay Kumar Gadamidi"

Article Synopsis
  • The study focuses on how the design of coronary stents and the blood flow conditions after they are placed impact the success of heart procedures and patient health.
  • An innovative algorithm for accurately creating 3D models of stents using intravascular ultrasound and angiography has been developed, showing high precision in complex stent configurations.
  • This method not only confirms its accuracy in silicone models but also proves useful in clinical settings for assessing blood flow dynamics, aiding in optimizing stenting techniques and stent innovations.
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Article Synopsis
  • Optical coherence tomography (OCT) is a crucial imaging technique for diagnosing coronary artery disease, but accurate segmentation of the lumen is challenging due to various image artifacts.
  • The research introduces a rapid automatic segmentation method that leverages nonuniform rational B-spline to effectively outline the OCT lumen edges while minimizing noise.
  • Tested on 3300 OCT frames from 10 patients, the method operates in just 0.17 seconds per frame and offers accurate lumen segmentation and vessel reconstruction, enhancing the evaluation of coronary artery morphology.
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Article Synopsis
  • The study focuses on improving the understanding and treatment of coronary bifurcation lesions by developing a new method for 3D reconstruction of their anatomy and plaque composition using intravascular ultrasound (IVUS) and angiography.
  • Researchers tested this method by creating patient-specific silicone models and comparing them against micro-computed tomography (µCT) for accuracy, finding a high level of agreement.
  • The proposed approach is efficient, taking under 60 minutes for reconstruction, and can aid in clinical planning and education regarding stenting strategies for complex coronary artery cases.
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Article Synopsis
  • Baclofen is a muscle relaxant that has been in use since 1977 and generally has few serious side effects when taken as prescribed.
  • A case was reported where a 20-year-old woman developed catatonia after overdosing on baclofen, experiencing symptoms like aphasia and mutism after taking 200 mg following a suicide attempt.
  • This is the first documented instance of baclofen-induced catatonia in a healthy individual, with past literature linking such episodes to prior psychotic symptoms; her condition improved with low-dose lorazepam treatment.
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Since the inception of the current pandemic, COVID-19 related misinformation has played a role in defaulting control of the situation. It has become evident that the internet, social media, and other communication outlets with readily available data have contributed to the dissemination and availability of misleading information. It has perpetuated beliefs that led to vaccine avoidance, mask refusal, and utilization of medications with insignificant scientific data, ultimately contributing to increased morbidity.

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Background: The high rate of transmission and infection of coronavirus disease 2019 (COVID-19) is a public health emergency of major epidemiological concern. No definitive treatments have been established, and vaccinations have only recently begun. We aim to review the efficacy and safety of Interferon Beta (IFN-β) in patients who have a confirmed COVID-19 diagnosis.

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