Publications by authors named "Vinay Byrappa"

Background: Endovascular mechanical thrombectomy (EMT) for acute ischemic stroke can be conducted under conscious sedation (CS) or general anesthesia (GA). Emergency conversion from CS to GA during the procedure can occur, but its predictors and impact on clinical outcomes are not fully understood.

Methods: A single centre retrospective analysis was conducted on 226 patients who underwent EMT for anterior circulation stroke.

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Multimodal intraoperative neurophysiological monitoring (IONM) is highly valuable in scoliosis surgeries for monitoring spinal cord function, particularly during instrumentation. Accurate timing of baseline recordings of TcMEP and SSEP is crucial, as any changes observed during surgery and instrumentation are compared to these baseline recordings. However, the impact of ultrasound-guided erector spinae block (USG-ESPB) on SSEP and TcMEP is not well-studied in scoliosis surgery.

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Background: When general anesthesia is used for endovascular thrombectomy (EVT) for acute ischemic stroke (AIS), the choice of anesthetic agents for maintenance remains inconclusive. The different effects of intravenous anesthetic and volatiles agents on cerebral hemodynamics are known and may explain differences in outcomes of patients with cerebral pathologies exposed to the different anesthetic modalities. In this single institutional retrospective study, we assessed the impact of total intravenous (TIVA) and inhalational anesthesia on outcomes after EVT.

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Background: Endovascular mechanical thrombectomy (EMT) is the standard of care for acute ischemic stroke (AIS) caused by proximal large vessel occlusions. There is conflicting evidence on outcome of patients undergoing EMT under procedural sedation (PS) or general anesthesia (GA). In this retrospective study we analyze the effect of GA and PS on the functional outcome of patients undergoing EMT.

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The capnography is an important monitor to assess the patient's respiratory status. Importance of education for clinicians in interpretation of alarms and various capnography waveforms in different clinical scenarios and equipment malfunction is an understatement. Capnography waveforms due to sample line tube leak is described well in literature.

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In patients with normal lung and reasonable cardiac function such as head injury patients, the PETCo can be used as a surrogate for partial pressure of Carbon dioxide (PaCO) in mechanically ventilated patients. Thus early interpretation and accurate assessment of capnogram is crucial in neurocritical care patients. Here we present and discuss a scenario where in connection of a jet nebulizer to the ventilator lead to abrupt decrease in end tidal carbon dioxide leading to a diagnostic dilemma.

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The integrity of inspiratory and expiratory unidirectional valves is very important in the normal functioning of an anesthetic circle breathing system. We describe our experience of an emergency manipulation of a ceramic valve disk of a circle breathing system (Dräger Fabius GS, Dräger Medical Inc) that altered its characteristics and led to rebreathing only during spontaneous ventilation.

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Identification and analysis of critical respiratory alarms during use of an advanced anesthesia workstation is essential in the intraoperative period. We present and discuss a scenario in which there was activation of a fresh gas flow alarm during low-flow anesthesia intraoperatively and use of oxygen flush to counteract it led to a diluted concentration of the inspired anesthetic agent.

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Background: Non-neurological complications like acute kidney injury (AKI) can affect outcome of traumatic brain injury (TBI). This study aims to analyze the incidence, predictive factors, and impact of AKI in operated patients with severe TBI.

Methods: We retrospectively reviewed the data of 395 patients who underwent surgery for severe TBI and survived to be discharged from the hospital over a 1-year period.

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Understanding the functioning of modern anesthesia workstations is very important because workstation failures in the intraoperative period may place the patient at risk of perioperative hypoxia and lead to unnecessary anxiety and confusion among anesthesia care providers. We present and simulate a critical event leading to Dräger Fabius GS ventilator failure.

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Airway pressure monitoring is critical in modern day anesthesia ventilators to detect and warn high or low pressure conditions in the breathing system. We report a scenario leading to unexpectedly very high peak inspiratory pressure in the intraoperative period and describe the mechanism for high priority alarm activation. We also discuss the role of a blocked bacterial filter in causing sustained display of increased airway pressure.

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Ventriculo peritoneal (VP) shunt uncommonly complicates as intracranial hematomas which can still occur in patients with a functioning VP shunt leading to a delay in the diagnosis which can be extremely dangerous and lead to adverse outcomes. We report a case of an incidental diagnosis of delayed post-operative EDH following VP shunt in an young adult patient with a right cerebellar lesion and highlight the need for meticulous post-operative neurological examination.

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Following an episode of reduction in inspired oxygen concentration (FiO(2)) and inhalational agent concentration (Fi agent) during the changing of a soda lime absorber, We conducted an in vitro experiment to understand the impact of disconnection of the absorber on inspired gas dilution at different fresh gas flows. We found that both in Dräger Fabius GS and Primus anaesthesia work stations, disconnection of the absorber caused progressive reduction in FiO(2) and Fi agent as the FGF was decreased. The operating principle of fresh gas decoupling (FGD) valve is a potential source of this complication, which must be kept in mind while changing the soda lime during the course of surgery where an anaesthetic work stations utilizing FGD valves are used.

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Microsurgical excision and good anesthetic management of arteriovenous malformation (AVM) that ruptures during endovascular embolization can ensure good outcome despite per-procedural catastrophe. This case report illustrates the successful anesthetic management of microsurgical excision of ruptured AVM with entrapped microcatheter and highlights the role of the anesthesiologist in careful monitoring of the patient's hemodynamic status and communicating any changes to the radiology team to facilitate check angiography to diagnose the intracranial complication. This case highlights the need for anticipating and defining a catastrophe plan in advance of each interventional neuroradiology procedure as complications are rapid and require good multidisciplinary communication to ensure safe and successful outcomes.

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Objective: To analyze the anesthetic techniques used for sedation during magnetic resonance imaging (MRI) study of patients with Joubert syndrome (JS) and assess the safety and efficacy of these anesthetic regimens in these children.

Background: Joubert syndrome is a rare neurological disorder with significant anesthetic implications. This study describes the anesthetic management of children with JS undergoing MRI study with different anesthetic agents and implications of various anesthetic techniques in these patients.

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