Publications by authors named "Vinas M"

Paddy fields are a major anthropogenic source of global methane (CH) emissions, a powerful greenhouse gas (GHG). This study aimed at gaining insights of different organic and inorganic conductive materials (CMs) - biochar, fungal melanin, and magnetite - to mitigate CH emissions, and on their influence on key microbial populations, mimicking the postharvest season throughout the degradation of rice straw in microcosms under anaerobic conditions encompassing postharvest paddy rice soils from the Ebro Delta, Spain. Results showed that fungal melanin was the most effective CM, significantly reducing CH emissions by 29 %, while biochar amendment also reduced emissions by 10 %.

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Common beans (Phaseolus vulgaris L.) are widely consumed legumes in Latin America and Africa, valued for their nutritional compounds and antioxidants. Their high polyphenol content contributes to the antioxidant properties, with bioactive compounds showing antifungal and antimycotoxin effects.

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We describe here the first isolation in Argentina of a lactose-fermenting and lysine decarboxylase-negative non-Typhi Salmonella enterica from a blood culture of a patient with systemic lupus erythematosus. The microorganism was identified as S. enterica (score: 2.

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Salmonella spp. is one of the most important zoonotic pathogens that causes foodborne diseases. It is divided into two species (Salmonella bongori and Salmonella enterica) including around 2600 serovars, being S.

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  • A study was conducted to evaluate the effectiveness of the awake-prone position for patients with COVID-19-related acute respiratory failure requiring high-flow nasal oxygen in Argentina.
  • The study included 728 patients across two waves of the pandemic, comparing outcomes like endotracheal intubation and in-hospital mortality between those in the awake-prone position and those in a non-prone position.
  • Results showed that the awake-prone position significantly reduced the risk of both endotracheal intubation and in-hospital mortality, with consistent benefits observed across different waves of the pandemic.
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Maize (Zea mays L.) is an important cereal crop worldwide. Contaminated maize kernels pose a significant mycotoxin exposure risk for humans in Latin America.

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Enhanced In Situ Bioremediation (EISB) using Emulsified Vegetable Oil (EVO) as a long-term electron donor has gained prominence for the treatment of groundwater contaminated with chlorinated ethenes (CEs). This study explores the potential of isotopic and molecular biology tools (MBT) to investigate the CEs (PCE, TCE and cis-DCE) bioremediation using EVO in a contaminated site. A multiple approach using C and Cl-CSIA, quantification of Dehalococcoides (Dhc) and specific reductive dechlorination (RD) gene population, and hydrochemical data in microcosm experiments and field samples was applied.

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Background: Moderate-to-severe atopic dermatitis (AD) can be difficult to manage in paediatric patients, and there are few licensed treatments available for this age group. Dupilumab is approved for the treatment of AD in children older than 6 months.

Objectives: To assess the effectiveness and safety of dupilumab in a real-world cohort of paediatric patients with AD in Spain.

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  • Molecular diagnosis in allergology, particularly using the ImmunoCAP ISAC 112 microarray, improves identification of specific allergens in patients, enhancing the understanding of their allergies.
  • A study conducted in Catalonia assessed this method's impact on diagnosis and treatment (specifically immunotherapy) in young patients with allergic conditions, showing significant shifts in treatment plans.
  • Results indicated that over half of the patients (51%) had changes in their immunotherapy prescriptions based on molecular diagnostic findings, suggesting this approach leads to better-targeted treatments.
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Peptides displaying antimicrobial properties are being regarded as useful tools to evade and combat antimicrobial resistance, a major public health challenge. Here we have addressed dendrimers, attractive molecules in pharmaceutical innovation and development displaying broad biological activity. Triazine-based dendrimers were fully synthesized in the solid phase, and their antimicrobial activity and some insights into their mechanisms of action were explored.

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Introducion: Fungal melanin is an underexplored natural biomaterial of great biotechnological interest in different areas. This study investigated the physical, chemical, electrochemical, and metal-binding properties of melanin extracted from the metallotolerant black fungus strain IRTA-M2-F10.

Materials And Methods: Specific inhibitory studies with tricyclazole and biochemical profiling of whole cells by synchrotron radiation-based Fourier-transform infrared spectral microscopy (SR-FTIRM) were performed.

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Atrial fibrillation is the most frequent chronic arrhythmia in patients with chronic kidney disease. Oral anticoagulation with vitamin K antagonists and now direct oral anticoagulants have been and are the fundamental pillars for the prevention of thromboembolic events. However, there are no randomized clinical trials on the risk-benefit profile of oral anticoagulation in patients with chronic kidney disease stage 5 on peritoneal dialysis and there is little evidence in the literature in this population.

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Background: Therapeutic orthodontic premolar extraction is a common orthodontic treatment, yet the extent of its impact on the upper dental arch dimensions and teeth angulations is still under exploration. Hypothesis: We postulated that the therapeutic extraction of orthodontic premolars significantly alters the orientation of teeth and the dimensions of the dental arch. Objective: This study assessed the impact of therapeutic orthodontic premolar extraction on dental arch dimensions and tooth angulations.

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A collection of 34 melanized fungi isolated previously from anthropogenic contaminated sites were assessed for their tolerance to toxic concentrations of As(V) and Cr(VI) anions. Three strains of the species , , and (Chaetothyriales) were identified as hyper-metallotolerant, with estimated IC values that ranged from 11.2 to 16.

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  • * The study involved 60 osteotomy site preparations, with equal groups using either the AR device or the conventional method, and both methods were assessed using preoperative and postoperative imaging.
  • * Results showed no significant differences in accuracy between the AR technique and the conventional method for coronal, apical, and angular deviations in osteotomy sites.
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This work studied the potential of a combination of pungent spices (capsicum, black pepper, ginger, and cinnamaldehyde) to be used as a supplement in diets of gilthead seabream (; 44.1 ± 4.2 g).

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Biofilms are responsible for the most prevalent oral infections such as caries, periodontal disease, and pulp and periapical lesions, which affect the quality of life of people. Antibiotics have been widely used to treat these conditions as therapeutic and prophylactic compounds. However, due to the emergence of microbial resistance to antibiotics, there is an urgent need to develop and evaluate new antimicrobial agents.

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Cationic antimicrobial peptides are molecules with potential applications for treating infections due to their antimicrobial and immunomodulatory properties. The aim of this work was to explore the antimicrobial activity and mechanisms of action of a porcine neutrophil cathelicidin mixture (MPPN). Gram-positive and Gram-negative bacteria were used to determine the minimum inhibitory concentration (MIC) and experiments of both time-kill kinetics and effects on growth curves were performed.

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Introduction: To overcome the challenge of multidrug resistance, natural and synthetic peptides are candidates to become the basis of innovative therapeutics, featuring diverse mechanisms of action. Traditionally, the time elapsed from medical discoveries to their application is long. The urgency derived from the emergence of antibiotic resistance recommends an acceleration of research to put the new weapons in the hands of clinicians.

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Given their role in lipid digestion, feed supplementation with bile salts could be an economic and sustainable solution to alterations in adiposity and intestinal inflammation generated by some strategies currently used in aquaculture. An important part of the metabolism of bile salts takes place in the intestine, where the microbiota transforms them into more toxic forms. Consequently, we aimed to evaluate the gut immune response and microbial populations in gilthead seabream () fed a diet supplemented with a blend of bile salts with proven background as a regulator of lipid metabolism and fat content.

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The emergence of multidrug-resistant Pseudomonas aeruginosa infections has urged the need to find new strategies, such as the use of combinations of antibiotics. Among these, the combination of colistin with other antibiotics has been studied. Here, the action of combinations of colistin and rifampicin on both planktonic and sessile cells of colistin-resistant P.

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New antibiotic agents were prepared using Povarov and Ugi multicomponent reactions upon the known drugs sulfadoxine and dapsone. The prepared derivatives, with increased lipophilicity, showed improved efficiency against Mycolata bacteria. Microbiological guidance for medicinal chemistry is a powerful tool to design new and effective antimicrobials.

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We evaluated the interaction of multifocal patterns with eye's accommodation. Seven patterns were mapped on the spatial light modulator and the deformable mirror of an adaptive optics visual simulator, and projected onto the subjects' eyes, representing different contact lens designs: NoLens, Bifocal Center Distance (+2.50D), Bifocal Center Near (+2.

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Background: The efficacy of mouth-rinses strongly depends upon their substantivity. The use of natural and non-toxic products that avoid secondary effects is gaining interest in preventive dentistry. The purpose of this study was to evaluate the substantivity of two formulations of mouth-washing solutions based on cetylpyridinium (CPC) and O-cymen-5-ol.

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  • The study investigates using wood pellets and granulated cork as carbon sources in biofilters for over 400 days, focusing on their effectiveness in removing nitrates and pesticides under different moisture conditions.
  • The findings reveal that water-saturated wood biofilters were highly effective (>99% nitrate removal) while cork biofilters struggled, with both types showing good pesticide removal rates, particularly for mecoprop and diuron.
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