Publications by authors named "Vilma T Viana"
Objectives: To evaluate long-term effects on gamma-globulins and autoantibodies of abatacept (ABA) versus tumor necrosis factor inhibitors (TNFi) in rheumatoid arthritis (RA) patients.
Method: Eighteen RA patients undergoing abatacept (ABA-RA) and 18 age/sex-matched patients treated with TNFi (TNFi-RA) were compared regarding clinical data, total gamma-globulins (TGG), specific subtypes (IgG, IgM, IgA), free light chains (FLC), IgM/IgG rheumatoid factor (RF), anti-cyclic citrullinated peptide (anti-CCP3), and anti-mutated citrullinated vimentin (anti-MCV), assessed before and every 6 months, up to 24 months.
Exclusion Criteria: previous abatacept/rituximab or low TGG (< 0.
Article Synopsis
- This study aimed to investigate whether serum uric acid (SUA) levels can predict long-term kidney outcomes in patients with lupus nephritis (LN) after 7 years of follow-up.
- A total of 80 LN patients were analyzed, with SUA levels measured at baseline, 6 months, and 12 months; the study found that SUA levels at 12 months were statistically significant in differentiating good and poor renal outcomes.
- The research concluded that SUA levels below 6.05 mg/dL at the 12-month mark indicate a better prognosis for kidney health in LN patients over the long term.
Objectives: To assess IgM anti-alpha-enolase antibodies (AAEA) in systemic Behçet's disease (BD) and its possible association with clinical manifestations and disease activity.
Methods: Ninety-seven consecutively selected BD patients were compared to 36 enteropathic spondyloarthritis (ESpA) [24 Crohn's disease (CD) and 12 ulcerative colitis (UC)] patients and 87 healthy controls. IgM AAEA was detected by immunoblotting.
Background: Advances in pathophysiology and treatment of ankylosing spondylitis (AS) was recently demonstrated. However, the effect of anti-TNF in the newly described inflammatory pathways involved pathogenesis of this disease remains to be determined. The aim of our study was, therefore, to investigate long-term influence of anti-TNF drugs in IL-23/IL-17 axis of AS patients and their possible correlation with treatment, clinical, laboratory and radiographic parameters.
View Article and Find Full Text PDF