Publications by authors named "Villegas-Silva R"

Background: Respiratory distress syndrome (RDS) is Mexico's second leading cause of neonatal mortality. The 75% reduction in mortality due to RDS has been attributed to the use of nasal continuous positive airway pressure (nCPAP). A survey was conducted to determine the perception of the medical staff regarding the availability of nCPAP equipment and supplies in Mexican hospitals with neonatal intensive care units (NICUs).

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Necrotizing enterocolitis (NEC) is an inflammatory bowel disease and a leading cause of morbidity and mortality in preterm infants. In this study, a randomized double-blind parallel-group (1:1) trial was carried out in two neonatal intensive care units of two tertiary hospitals. Two hundred and twenty-five preterm newborns with an expected functional gastrointestinal tract were recruited and received an enteral dose of 75 mg of docosahexaenoic acid (DHA)/kg body weight or high-oleic sunflower oil daily for 14 days from the first enteral feed after birth.

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Background: On March 11, 2020, the World Health Organization declared the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic, and on February 28, Mexico reported its first case. Internationally, cases in newborns are few and the outcomes, in general, are good. There is no certainty of possible vertical transmission, and the presence of the virus in human milk is improbable.

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Background: Echocardiography is useful in the group of comorbidities of critically ill newborns. The targeted neonatal echocardiography program trains neonatologists for acquiring and interpreting hemodynamic variables to support decision making. This study aimed to describe the results of the functional echocardiography program (fNE) and compare clinical and hemodynamic variables between survivors and non-survivors.

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Background: Retinopathy of prematurity (ROP) is a disorder of the retina of low-birth-weight preterm infants that potentially leads to blindness. Docosahexaenoic acid (DHA), is protective in experimental models, but its administration as part of parenteral nutrition has shown inconsistent results. We test the effect of enteral DHA to prevent ROP and/or severity and to reduce hospital stay.

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Objective: Gastroschisis incidence is rising. Survival in developed countries is over 95%. However, in underdeveloped countries, mortality is higher than 15% often due to sepsis.

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Background: Neonates undergoing surgery require analgesic medication to ameliorate acute pain. These medications produce negative side effects. Docosahexaenoic acid (DHA) has an antinociceptive effect in animals, but this has not been evaluated in human neonates.

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Background: Neonates undergoing surgery are at risk for uncontrolled inflammatory response and adverse clinical outcomes. Docosahexaenoic acid (DHA) ameliorates inflammation, improving clinical outcomes. However, its effect has not been evaluated in neonates undergoing surgery.

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Background: Hospital-grade electric pumps may be useful to initiate and sustain adequate milk production for mothers who are unable to breast-feed their babies hospitalized at special care nurseries (SCN), but their cost is generally not affordable for SCN and for most mothers in developing countries. Therefore, manual breast pumps (MBPs) can be an alternative, but the best option is unknown considering clinical parameters and mothers' preference from among currently available MBPs.

Objective: To compare the effectiveness of four MBPs in terms of milk volume, nutritional composition, and breast emptying in order to assist in making a choice for health care personnel and mothers in SCN settings.

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Objective: To identify risk factors associated to surgical site infection (SSI) in newborns.

Design: Case-control study. Site.

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Background: Serratia marcescens is a well-recognized nosocomial pathogen. The objective of the study was to describe typing results using a rapid pulsed field gel electrophoresis (PFGE) protocol and infection control measures during an outbreak of Serratia marcescens in a 24-bed, referral, neonatal intensive care unit (NICU) of a tertiary-care pediatric hospital.

Methods: Two patients with S.

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Unlabelled: The objective was to identify prognostic factors associated with mortality in newborns with congenital diaphragmatic hernia.

Methods: Study design was cases and controls nested in a cohort. We studied 65 newborns.

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Objective: To identify morbidity and mortality in newborns with congenital defects of the anterior abdominal wall.

Design: Descriptive, comparative, and retrospective study.

Patients: Thirty nine patients with gastroschisis and 26 patients with omphalocele.

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Objective: To report survival of newborns with congenital heart disease who underwent cardiac surgery during neonatal period.

Design: Descriptive, ambispective.

Setting: Neonatal Intensive Care Unit (NICU), Hospital de Pediatría, Centro Médico Nacional Siglo XXI.

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Objective: Elaborate and assess the degree of validity of a prognostic model for evaluating patients admitted to the Neonatal Intensive Care Unit (NICU).

Design: Cases and controls nested in a cohort.

Setting: NICU of two tertiary hospitals and another second level hospital.

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Objective: To determine sensitivity (Sn), specificity (Sp), positive and negative predictive values (PPV, NPV) of total and calculated calcium and of QTc and QoTc intervals for the diagnosis of hypocalcemia in critically ill newborns.

Setting: A neonatal intensive care unit.

Methods: We included all newborn less than 28 days of age; we excluded those with calcium treatment, hypomagnesemia or congenital heart disease.

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Objective: To analyze an outbreak of Serratia marcescens in a neonatal intensive care unit and identify the risk factors associated to the development of infection.

Material And Methods: It was a case-control study from March to July 1995. Factors included were age, sex, intravascular devices, nebulizers, mechanical ventilation, use of total parenteral nutrition (TPN), underlying diseases, surgical interventions, tubes, previous antimicrobial treatment and days of exposure.

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Objective: To assess the frequency and type of complications during central venous catheter installation by subclavian puncture, and during its use in children admitted to an ICU.

Patients And Methods: Patients from one month to 15 years of age, admitted to the Intensive Care Unit of the Hospital de Pediatría Centro Médico Nacional, Siglo XXI, who underwent a percutaneous infraclavicular subclavian puncture for central venous catheter complications were included. Clinical features, diagnosis, complications and indications for the procedure were registered.

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We analyzed 56 cases of children with diagnosis of poisoning, which were attendant at the pediatric emergency room at "Dr. Manuel Gea Gonzalez" General Hospital, during a period between October 1st 1987 and September 31st, 1988. A greater incidence among infants below 5 years of age was observed, 16.

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A study is made of the environmental, etiologic, pathogenic, clinical and anatomical characteristics of the bacterial or parasitic enteral processes which most frequently cause death to the patients. Considerations on the pathogenesis of the complications found at the postmortem studies in children with diarrhea are likewise offered.

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The clinical and anatomicopathological characteristics of acute and chronic toxoplasmosis are described as they affect different structures and systems. The lesion to adrenal glands is compared to that seen in disseminated herpes simplex; however, the question remains as to why in both congenital infections, necrosis of adrenal glands appears without inflammatory reaction. The investigation of special techniques for localization and identification of Toxoplasma gondii "groups" or cysts, leads to the conclusion that Grocott's silver impregnation technique used for the identification of Entamoeba histolytica is also useful to discover Toxoplasma in tissues.

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