[Delayed diagnosis of osteosarcoma in adults: a prognostic factor to be considered].

Introduction: different variables have been associated with a worse prognosis of patients with osteosarcoma (OS), highlighting tumor size, location in the axial skeleton and the presence of metastases. The objective of this study is to analyze the prognostic impact of diagnostic delay in osteosarcoma in adults in the Mexican population in a center specialized in sarcomas.

Material And Methods: retrospective cohort study from January 1, 2005, to December 31, 2016, 96 patients over 21 years of age with a diagnosis of osteosarcoma were analyzed.

[Prognostic factors associated with failure of modular knee arthroplasty in oncologic patients].

Introduction: reconstruction of large bone defects using modular knee arthroplasty (MKA) presents a significant challenge in terms of functionality. The objective of the present work was to identify the different prognostic factors associated with failure of MKA in cancer patients.

Material And Methods: a retrospective cohort study was conducted, including patients with a diagnosis of musculoskeletal tumor in the distal femur or proximal tibia, who underwent MKA between January 1, 2010, and December 31, 2021.

Acrometastasis: The Tip of the Iceberg of Metastatic Disease from Thyroid Cancer. Two Cases Report.

Acrometastasis, especially in the hands and fingers, is a rare clinical condition resulting from primary cancers such as lung, breast, kidney, and, rarely, thyroid cancer. Acrometastasis tends to be the tip of the iceberg in patients with extensive systemic disease, which could be regional, pulmonary, skeletal, neurological, or all of them combined. Even though these tumors are clearly visible and symptomatic, the diagnosis is usually misleading because such distal metastatic disease is not thought of at first.

[Initial surgical management of squamous carcinoma of the vulva].

Vulvar cancer accounts for approximately 4% of gynecological malignancies. At the Instituto Nacional de Cancerologia in Mexico it occupies the fourth place. The purpose of this study is to assess the management of squamous carcinoma of the vulva with initial surgical treatment.

Adenoid Cystic Carcinoma in a Mexican Population.

Objective: To analyze the demographic data, clinical behavior, management (surgery/radiotherapy), disease-free survival (DFS) and overall survival (OS) in Mexican Mestizos with adenoid cystic carcinoma (ACC).

Material And Methods: A retrospective study comprising all cases with histologic diagnosis of ACC of the head and neck treated from 1986 to 2012.

Results: There were 101 cases (69 women and 32 men), with a mean age of 50 years; mean evolution time before diagnosis was 25 months (range 1-180 months).

Comparative study between two different staging systems (AJCC TNM VS BALLANTYNE'S) for mucosal melanomas of the Head & Neck.

Background: Mucosal melanoma (MM) of head and neck (H&N) is a rare entity with a quite poor prognosis. Ballantyne's staging system has been commonly used since 1970. In the 7th edition of the AJCC Staging Manual a new chapter for the staging of TNM Classification system for mucosal melanoma (MM) of the head and neck (H&N) has been introduced to reflect the particularly aggressive biological behavior of this neoplasm.

Induction chemotherapy followed by supracricoid partial laryngectomy (SCPL) with cricohyoidoepiglottopexy (CHEP) in T3NO arytenoid fixation-related glottic cancer.

Unlabelled: Induction chemotherapy followed by supracricoid partial laryngectomy (SCPL) with cricohyoidoepiglottopexy (CHEF) in T3NO arytenoid fixation-related glottic cancer.

Objective: Arytenoid fixation in the larynx has been considered a contraindication for performing organ preservation surgery (OPS). We present a retrospective series of cases of arytenoid fixation-related T3N0 glottic cancer treated by neoadjuvant chemotherapy followed by OPS.

Conjunctival melanoma: survival analysis in twenty-two Mexican patients.

Purpose: To describe the cases of conjunctival melanoma (CM) and report the disease-free interval (DFI) and overall survival (OS).

Methods: The charts of 22 patients who were admitted to two hospitals between 1985 and 2006 were reviewed for pertinent data, including demographics, site of involvement in the conjunctiva and sub-sites, surgical treatment, and adjuvant treatment.

Results: There were 10 (45.

Uterine sarcomas: review of 26 years at The Instituto Nacional de Cancerologia of Mexico.

Unlabelled: Uterine sarcomas are a group of uncommon tumors that account for approximately 1% of malignant neoplasms of the female genital tract and between 3 and 8.4% of malignant uterine neoplasms.

Objective: To evaluate the factors associated with the clinical behavior of uterine sarcomas.

[Hypothyroidism incidence after multimodal treatment for laryngeal cancer].

Background: Hypothyroidism following total laryngectomy or radiotherapy treatment for laryngeal cancer is not a rare event, especially in advanced stages. There are no reports on the incidence of hypothyroidism in patients who received chemotherapy and radiotherapy. The objective of this study is to determine the incidence of thyroid dysfunction in a group of patients with laryngeal cancer who underwent surgery as sole treatment, total laryngectomy or radiotherapy alone, and patients with combined treatment: surgery plus radiotherapy, concomitant chemoradiation therapy and chemoradiation therapy plus salvage surgery.

Upper lip malignant neoplasms. A study of 59 cases.

Objectives: To present the demographic data, clinico-pathologic features and therapeutic outcome of a series of upper lip malignancies.

Study Design: Retrospective study at a single Cancer Institution in Mexico City during a 14-year period.

Results: There were 59 cases, (30 males and 29 females); age range: 14 to 106 years (mean: 73 yr.

[The first Mexican consensus of endometrial cancer. Grupo de Investigación en Cáncer de Ovario y Tumores Ginecológicos de México].

Introduction: Endometrial cancer (EC) is the second most common gynecologic malignancy worldwide in the peri and postmenopausal period. Most often for the endometrioid variety. In early clinical stages long-term survival is greater than 80%, while in advanced stages it is less than 50%.

[Laryngeal cancer in patients younger vs older than 40 years old: a matched-paired analysis].

Background: To compare clinical and demographic data between laryngeal cancer patients younger and older than 40 years old.

Methods: Is a matched-paired study, realized from 1989 to 2002. We selected 500 laryngeal cancer patients treated in the National Cancer Institute of Mexico.

Osteogenic sarcoma of the maxillary region in a Mexican mestizo population.

Background And Objectives: This study analyzed maxillary osteosarcoma in a mestizo population, with particular emphasis on the type of treatment and disease-free and overall survival.

Methods: This is a retrospective study including all mestizo patients with osteosarcoma of the maxilla seen in a single cancer institution in Mexico during a 20-year period.

Results: There were 21 patients.

Vertical partial hemilaryngectomy with reconstruction by false cord imbrication.

Background: To evaluate global survival, disease-free period, complications, evolution and function in vertical partial hemilaryngectomy (VPHL) plus reconstruction with false cord.

Methods: Descriptive and retrospective study. In aertiary care medical center in Mexico City.

Supracricoid partial laryngectomy with cricohyoidoepiglottopexy in patients with radiation therapy failure.

Background: To assess functional results, complications, and success of larynx preservation in patients with recurrent squamous cell carcinoma after radiotherapy.

Methods: From a database of 40 patients who underwent supracricoid partial laryngectomy (SCPL) with cricohyoidoepiglottopexy (CHEP) from June 2001 to April 2006, eight patients were treated previously with radiotherapy due to squamous cell carcinoma of the glottic region and were treated for recurrence at the site of the primary cancer.

Results: SCPL with CHEP was performed in six men and two women with a mean age of 67 years due to recurrence and/or persistence at a mean time of 30 months postradiotherapy (in case #8 after concomitant chemoradiotherapy).

Demographic data of laryngeal cancer at the Instituto Nacional de Cancerología in Mexico City.

Background: We undertook this study to describe the demographic data of patients with laryngeal cancer treated at the Instituto Nacional de Cancerología in Mexico City.

Methods: We retrospectively reviewed the clinical files from 1986 to 2002, revealing 500 patients.

Results: Included were 452 men (90.

Carotid body tumour resection with LigaSure device.

Objective: We carried out this study in patients who underwent resection of carotid body tumour (CBT). Shamblin's classification system was used as well as the modified Shamblin classification. We sought to determine whether surgical time and bleeding could be reduced with the use of the LigaSure system.

Adenoid cystic carcinoma of the tongue--clinicopathological study and survival analysis.

Background: To review the demographic data of a series of adenoid cystic carcinoma (ACC) of the tongue, as well as to analyze c-kit expression, histopathologic patterns, prognostic factors, evolution, recurrences and/or persistence and survival.

Methods: Retrospective study from 1986 to 2006, which reviews a database of 68 patients with diagnosis of head and neck ACC.

Results: We found eight cases of ACC of the tongue (11.

Primary retroperitoneal mucinous cystadenocarcinoma: report of two cases.

Background: Retroperitoneal cystadenocarcinomas are rare lesions, the majority of cases presented as one-patient reports.

Methods: We present two cases of retroperitoneal cystadenocarcinoma, both in women of reproductive age: one with aggressive behavior, and the remaining case, with a more indolent clinical evolution.

Results: One case presented as pelvic tumor, was treated with surgical resection of the disease, but manifested with recurrent disease a few months later despite use of chemotherapy.

Control of Frey's syndrome in patients treated with botulinum toxin type A.

Aim: To identify the severity of Frey s syndrome and its response to botulinum toxin type A.

Methods: Minor test was performed in all cases to assess the extent of the affected area, using the contralateral side as control. Severity was assessed according to the proposal of Luna-Ortiz et al.

[Laryngeal cancer in patients younger than 40 years].

Background: We undertook this study to report demographic data of laryngeal cancer patients <40 years old and treatment results.

Methods: In a retrolective study we reviewed the clinical records of 500 patients with laryngeal cancer in the period from 1989 to 2004 and included those patients<40 years of age.

Results: We found 15 patients, representing 4.

Craniofacial resection for sinunasal tumors.

Introduction: Malignant sinonasal tumors are very rare in Mexico. They ussually present as advanced disease because it is extremely difficult to make an early diagnosis; in addition, its treatment is complicated by a variety of lesions. Surgical resection remains the mainstay of treatment, but its relative therapeutic value compared with alternative treatments is controversial.