Publications by authors named "Viljakka M"
Importance: Severe obesity is a major health concern. However, a few patients remain resistant to bariatric surgery and other treatments. Animal studies suggest that weight may be altered by fecal microbiota transplantation (FMT) from a lean donor.
View Article and Find Full Text PDFPurpose: This study was undertaken to evaluate the efficacy and safety of laparoscopic repair for rectal prolapse.
Methods: A case-control study was undertaken. The case group consisted of a consecutive series of patients who underwent laparoscopic repair for rectal prolapse between February 1993 and June 2000.
Objective: To evaluate the influence of antireflux surgery on gastric emptying.
Design: Nonrandomized controlled trial 3 months before and after surgical intervention.
Setting: Secondary and tertiary referral center.
Background: Open or laparoscopic surgery for gastroesophageal reflux disease gives longterm freedom from symptoms in 83-100% of cases but has a certain percentage of complications. This study was undertaken to evaluate the early and late complication rates after primary or repeat antireflux operations.
Study Design: The records of all patients who underwent surgery for gastroesophageal reflux disease during a 32-year period at a university teaching hospital were reviewed retrospectively.
Lifetime costs of surgical versus medical treatment of severe gastro-oesophageal reflux disease in Finland.
Scand J Gastroenterol
August 1997
Background: Gastro-oesophageal reflux disease (GERD) can be effectively treated pharmacologically or surgically. As GERD is often a chronic condition, we compared the long-term costs of medical and surgical management.
Methods: The medical regimens were ranitidine (150 or 300 mg/day), omeprazole (20 or 40 mg/day), and lansoprazole (30 mg/day), with costs calculated for total life expectancy after diagnosis and for one-third of that time.
Background: The advent of proton-pump inhibitors, and subsequently of the laparoscopic technique, can be assumed to have influenced the use of antireflux surgery in gastro-oesophageal reflux disease.
Methods: Data on antireflux operations carried out in Finland in 1988-93 were obtained from national statistics, and the number of operations performed laparoscopically in 1993 was ascertained by a questionnaire to all relevant units. The rates per 100,000 population in the catchment areas were calculated.
Background: The main cause of recurrent reflux symptoms after Nissen fundoplication is disruption of the fundic wrap. Reoperation has shown a lack of scar tissue between the serosal surfaces of the fundic folds in these cases.
Methods: Attempts were made to induce serosal scarring during fundoplication performed in rabbits.
Objective: The purpose of the study was to evaluate the long-term symptomatic and endoscopic outcome in gastroesophageal reflux disease with erosive esophagitis, comparing conservative with operative management.
Methods: The study comprised 105 of 120 patients consecutively referred for severe reflux symptoms to the gastroenterologic outpatient department of a teaching hospital, where erosive esophagitis was confirmed endoscopically. If conservative management (modified lifestyle and medication) failed to relieve symptoms and heal the esophagitis, antireflux surgery (Nissen fundoplication) was undertaken.
Natural course of gastroesophageal reflux disease: 17-22 year follow-up of 60 patients.
Am J Gastroenterol
January 1997
Objective: To elucidate the long-term course of conservatively managed gastroesophageal reflux disease without H2-antagonists or omeprazole.
Design: Clinical trial, uncontrolled.
Setting: Gastroenterological outpatient department of a teaching hospital.