Recombinant factor VIIa in the management of postpartum bleeds: an audit of clinical use.

Background: This paper presents an analysis of 25 patient cases in which recombinant factor VIIa was used in the management of postpartum hemorrhage, including severe and/or life-threatening bleeds. Anecdotal experiences in the empirical use of this agent are described and dosing regimens, effects on bleeding, and safety data are presented.

Methods: Data were extracted from the international, internet-based, voluntary registry, haemostasis.