Publications by authors named "Vildan Sultanaev"
The growing resistance of pathogens, bacteria, viruses, and fungi to a number of drugs has encouraged researchers to use natural and synthetic biomimetic systems to overcome this challenge. Multicomponent systems are an attractive approach for drug design and multitarget therapy. In this study, we report the assembly of a three-component (pillar[5]arene, bovine serum albumin, and methyl orange) biosupramolecular system as a potential drug delivery system.
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- Researchers developed new pH-responsive drug carriers using decasubstituted pillar[5]arene derivatives with amino acids -Tryptophan and -Phenylalanine.
- The study examined how these carriers release a fluorescent dye at various pH levels, finding that -Tryptophan-based carriers released the dye at neutral and alkaline pH, while -Phenylalanine-based carriers did not release it at all.
- The findings suggest that pillar[5]arene derivatives with amino acid fragments could be effective for targeted drug delivery in biomedicine, particularly at the cellular level due to their small size.