Publications by authors named "Viktoryia I Kulikouskaya"
Article Synopsis
- * The treatment did not alter the functional groups of the polysaccharides but did change their monosaccharide composition and morphology, enhancing their anti-photoaging properties.
- * The most effective polysaccharide, DSFP-45, significantly increased cell viability and collagen production while reducing inflammatory cytokines in UVB-irradiated human skin cells, indicating potential for new anti-photoaging drugs or functional foods from seaweed.
Honeycomb-Structured Porous Films from Poly(3-hydroxybutyrate) and Poly(3-hydroxybutyrate--3-hydroxyvalerate): Physicochemical Characterization and Mesenchymal Stem Cells Behavior.
Viktoryia I Kulikouskaya Viktoryia V Nikalaichuk Anton P Bonartsev Elizaveta A Akoulina Nikita V Belishev
Polymers (Basel)
June 2022
Surface morphology affects cell attachment and proliferation. In this research, different films made of biodegradable polymers, poly(3-hydroxybutyrate) (PHB) and poly(3-hydroxybutyrate--3-hydroxyvalerate) (PHB--HV), containing different molecular weights, with microstructured surfaces were investigated. Two methods were used to obtain patterned films-water-assisted self-assembly ("breath figure") and spin-coating techniques.
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- Layer-by-Layer assembled polyelectrolyte films utilize negatively charged biopolymers and positively charged polysaccharides to influence cell attachment and behavior on surfaces.
- The study focused on the properties of these films, particularly those containing chitosan, which exhibited linear growth, smooth surfaces, and viscoelastic characteristics, while films with polyethyleneimine showed increased rigidity and roughness.
- When tested with mesenchymal stem cells, chitosan films promoted effective cell adhesion and high viability, suggesting that the stiffness and surface properties of these films are crucial for tissue engineering applications.