Publications by authors named "Viktoriya G Yankova"

β-tricalcium phosphate (β-TCP) is a promising material in regenerative traumatology for the creation of bone implants. Previously, it was established that doping the structure with certain cations can reduce the growth of bacterial activity. Recently, much attention has been paid to co-doped β-TCP, that is explained by their ability, on the one hand, to reduce cytotoxicity for cells of the human organism, on the other hand, to achieve a successful antibacterial effect.

View Article and Find Full Text PDF

Addressing periprosthetic infections, which present significant healing challenges that often require revision surgeries, necessitates the development of novel antibacterial materials and implants. Current research focuses on creating materials that hinder bacterial adhesion, colonization, and proliferation in surrounding tissues. Boron (B)-containing compounds are known for their antibacterial properties and potential in bone metabolism for regenerative medicine.

View Article and Find Full Text PDF

An alternative approach for the currently used replacement therapy in dentistry is to apply materials that restore tooth tissue. Among them, composites, based on biopolymers with calcium phosphates, and cells can be applied. In the present work, a composite based on polyvinylpyrrolidone (PVP) and alginate (Alg) with carbonate hydroxyapatite (CHA) was prepared and characterized.

View Article and Find Full Text PDF

Gadolinium-containing calcium phosphates are promising contrast agents for various bioimaging modalities. Gadolinium-substituted tricalcium phosphate (TCP) powders with 0.51 wt% of gadolinium (0.

View Article and Find Full Text PDF

Metered-dose nasal sprays (MDNS) are the most widely used for treating rhinitis. Medicinal preparations in the pharmaceutical market vary in their characteristics. To identify the most effective drug, it is necessary to compare the preparations regarding various parameters.

View Article and Find Full Text PDF
Article Synopsis
  • - PMMA bone cements are used to secure prostheses and are now being modified with antibacterial agents like gentamicin, peppermint oil, and silver nanoparticles to combat infections.
  • - The study involved analyzing the structure and properties of these modified cements using techniques such as SEM, EDS, and MTT assays to assess toxicity and biocompatibility.
  • - Results indicated that the addition of antimicrobial agents did not compromise the cements' hydration or degradation, and showed effective antimicrobial properties, highlighting their potential for clinical use against infections.
View Article and Find Full Text PDF

New materials are required for bone healing in regenerative medicine able to temporarily substitute damaged bone and to be subsequently resorbed and replaced by endogenous tissues. Taking inspiration from basic composition of the mammalian bones, composed of collagen, apatite and a number of substitution ions, among them magnesium (Mg), in this work, novel composite scaffolds composed of collagen(10%)-hydroxyapatite (HAp)(90%) and collagen(10%)-HAp(80%)-Mg(10%) were developed. The lyophilization was used for composites preparation.

View Article and Find Full Text PDF