Publications by authors named "Viktoriia Horbas"
Breast cancer (BC) continues to be a significant global challenge due to drug resistance and severe side effects. The increasing prevalence is alarming, requiring new therapeutic approaches to address these challenges. At this point, Extracellular vesicles (EVs), specifically small endosome-released nanometer-sized EVs (SEVs) or exosomes, have been explored by literature as potential theranostics.
View Article and Find Full Text PDFIntroduction: Multiple system atrophy (MSA) is a rapidly progressive neurodegenerative disorder characterized by the presence of glial cytoplasmic inclusions (GCIs) containing aggregated α-synuclein (α-Syn). Accurate diagnosis and monitoring of MSA present significant challenges, which can lead to potential misdiagnosis and inappropriate treatment. Biomarkers play a crucial role in improving the accuracy of MSA diagnosis, and phosphorylated α-synuclein (p-syn) has emerged as a promising biomarker for aiding in diagnosis and disease monitoring.
View Article and Find Full Text PDFTumor progression and eradication have long piqued the scientific community's interest. Recent discoveries about the role of chemokines and cytokines in these processes have fueled renewed interest in related research. These roles are frequently viewed as contentious due to their ability to both suppress and promote cancer progression.
View Article and Find Full Text PDFArticle Synopsis
- Personalized medicine is advancing with RNA therapy, providing new treatment options for cardiovascular diseases (CVD) by targeting the human genome.
- Current research shows promise in using RNA therapies for diagnosing and preventing heart-related conditions, but only a few treatments are in clinical trials or FDA-approved.
- Key challenges include delivering drugs effectively to cells, managing immune responses, and ensuring overall safety, which need to be addressed for RNA therapies to progress.
Objective: The aim: To investigate the epidemiological and clinical characteristics of COVID-19 in children for the period 2020-2022.
Patients And Methods: Materials and methods: A retrospective analysis of 1144 case histories of children who were hospitalized at the St. Zinaida Children's Clinical Hospital (Sumy, Ukraine) for coronavirus disease for 2020-2022 was carried out.