Impact of intraoperative mechanical ventilation on left ventricular lead function in cardiac resynchronization therapy.

Background: Intraoperative controlled mechanical ventilation (CMV) changes the intrathoracic geometry and may impact postoperative left ventricular (LV) lead function after CRT implantation. This multicenter study investigates the effect of intraoperative ventilation setting (spontaneous breathing [SB] vs CMV) on postoperative LV lead function taking into account patients' body mass index (BMI).

Methods: CRT implantation was performed at two centers during SB in 92 and during CMV in 73 patients.