Publications by authors named "Viktoria Hoeller"
Article Synopsis
- The study investigates the link between arterial hypertension (HTN) and markers of left ventricular dysfunction and inflammation in patients with hypertrophic cardiomyopathy (HCM).
- It compares 30 HCM patients with HTN to 30 without, assessing echocardiographic measures and inflammatory markers.
- Results reveal that while both groups had similar cardiac function, those with HTN showed higher levels of systemic inflammation, suggesting HTN's negative effects on HCM patients stem from overall body inflammation rather than direct heart function decline.
Pivotal outcome trials targeting heart failure with preserved (HFpEF) and mildly-reduced ejection fraction (HFmrEF) may have excluded patients at highest risk of poor outcomes. We aimed to assess eligibility for HFpEF/HFmrEF outcome trials in an unselected heart failure cohort and its association with all-cause mortality. Among 32.
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- * Analyzed data from 102 patients revealed that Perugini scores of 2 or higher had a specificity of 95% and a positive predictive value (PPV) of 96% for diagnosing ATTR, while excluding patients with monoclonal proteins raised the PPV to 100%.
- * The study concluded that a non-invasive diagnosis of ATTR CA is reliable with a Perugini score ≥ 2 and a normal FLC, but a tissue biopsy is essential in
Amyloid light chain (AL) cardiomyopathy is the most malignant specific cardiomyopathy. According to international recommendations, it should be ruled out non-invasively using the serum free light chain (FLC) ratio and immunofixation electrophoresis in both serum and urine. Here, we report on a 69-year-old female patient with new-onset heart failure with mid-range ejection fraction.
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