Publications by authors named "Viktor F Mautner"
Article Synopsis
- Ependymomas are diverse tumors with specific types based on where they occur and their molecular characteristics, with spinal ependymomas (SP-EPN) being the most common type found in the spinal cord of both children and adults.
- Research revealed limited molecular data on SP-EPN, with known genetic changes including losses on chromosome 22q and mutations in NF2, but this study aimed to fill the gaps by analyzing transcriptomic, epigenetic, genetic, and clinical data from a large cohort.
- The study identified two subtypes of SP-EPN: subtype A, associated with known NF2 mutations and more severe disease, and subtype B, characterized by different genetic alterations and more stable NF2 expression, helping to
Sarcomas are malignant soft tissue and bone tumours affecting adults, adolescents and children. They represent a morphologically heterogeneous class of tumours and some entities lack defining histopathological features. Therefore, the diagnosis of sarcomas is burdened with a high inter-observer variability and misclassification rate.
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