A comparative study of the effect of different topical agents on burn wound infections.

Background: Topical agents are used to treat burn wound infections.

Aims And Objective: The present work was aimed to find out the in vitro efficacy of different topical agents against burn wound pathogens.

Settings And Design: Randomly selected gram-positive (29) and gram-negative bacterial (119) isolates from burn wound cases admitted in burn unit of Choithram Hospital and Research Centre, Indore, were included in the in vitro activity testing for silver nitrate, silver sulphadiazine (SSD), chlorhexidine, cetrimide, nitrofuran, soframycin, betadine, benzalkonium chloride and honey by growth inhibition on agar medium.

Ciprofloxacin therapy for typhoid fever needs reconsideration.

Outbreaks of multidrug-resistant Salmonella enterica serotype Typhi in the Indian subcontinent in the late 1980s resulted in the failure of conventional drugs, and ciprofloxacin became the firstline drug to treat enteric fever. However, reduced susceptibility to ciprofloxacin, reported widely since 1994, has posed a therapeutic difficulty. The aim of the present work was to review the situation of drug resistance among S.

Practical limitations of disinfection of body fluid spills with 10,000 ppm sodium hypochlorite (NaOCl).

The purpose of this study was to monitor disinfection with 10,000 ppm sodium hypochlorite for decontamination of common hospital spills. Simulated spills deliberately contaminated with 10(8) bacterial challenges were used for the study. Results showed greater than 5 log reduction in the challenge bacteria for all spills (serum, pus, sputum, csf, ascitic fluid, urine, and stool) except blood.