A Comparative Study of Intrathecal Hyperbaric Bupivacaine With Fentanyl Versus Intrathecal Hyperbaric Bupivacaine With Dexmedetomidine Administered Sequentially for Lower Limb Orthopaedic Surgeries: A Prospective Randomised Double-Blind Study.

Background:  The subarachnoid block is the predominant and relatively safe approach during lower limb orthopaedic operations. When used as an additive to intrathecal local anaesthetic, both fentanyl and dexmedetomidine can extend the duration of sensory and motor blockade and improve postoperative analgesia.

Objectives:  The objective of this study is to assess and compare the efficacy of sequential administration of fentanyl and dexmedetomidine alongside 0.

Use of Pregabalin as Preemptive Analgesia for Decreasing Postoperative Pain in Tympanoplasty.

Tympanoplasty is a commonly performed surgical procedure done by Otorhinolaryngologist for treatment of chronic suppurative otitis media. Postoperative period requires the use of analgesics which are given regularly. The study aims to assess the efficacy of a single dose of preemptive pregabalin in decreasing postoperative pain after postauricular type 1 tympanoplasty.

Clinical Analysis of Propofol, Etomidate and an Admixture of Etomidate and Propofol for Induction of General Anaesthesia.

Objective: To compare the clinical outcome following induction of general anaesthesia with intravenous (IV) injection of propofol (P), etomidate (E) or a 50% admixture of propofol and etomidate (PE).

Methods: In this prospective, randomised, double-blind controlled study, patients 18-60 years of age who were undergoing elective surgery with general anaesthesia were randomised to receive either propofol 2.5 mg kg IV (group P; n=30), etomidate 0.

A study of the efficacy of stellate ganglion blocks in complex regional pain syndromes of the upper body.

Background And Aims: The effect of stellate ganglion blocks (SGBs) was examined in complex regional pain syndromes (CRPS) of the upper body.

Material And Methods: A total of 287 SGB were given to patients with documented CRPS on medications. Spontaneous and provoked pain assessment was done with numeric pain rating scale (NPRS).

Keratoacanthoma centrifugum marginatum: unresponsive to oral retinoid and successfully treated with wide local excision.

We describe a case of a 65-year-old male presenting with a large plaque with a rolled-out interrupted margin, atrophic center, and island of normal skin over the left arm. It grew peripherally with central healing, and there was a history of recurrence after inadequate excision. Investigations ruled out other clinical mimickers; namely, squamous cell carcinoma, lupus vulgaris, botryomycosis, and blastomycosis-like pyoderma.

Toxic effects of pulp and paper-mill effluents on male reproductive organs and some systemic parameters in rats.

The effect of pulp and paper-mill effluents on terrestrial animals was investigated using male albino rats as a test organism, under controlled laboratory conditions. Effluent consumption for 15 days caused a reduction in the relative weight of the testis (mg/100g body weight), compared to the control rats. The effects were not so pronounced in other regions of the male reproductive tract.