Tolerability and efficacy of sacubitril/valsartan in clinical practice.

Background: Heart failure (HF) is a major cause of morbidity and mortality. Sacubitril/valsartan has demonstrated reductions in HF hospitalisation, and all-cause mortality in patients with heart failure with reduced ejection fraction.

Aims: To assess the tolerability and efficacy of sacubitril/valsartan in an intention to treat patient cohort.