Publications by authors named "Vikas Taneja"

Article Synopsis
  • Patients who receive organ transplants often need immunosuppressive medications, and this study aimed to explore the safety of biologic therapies like infliximab and adalimumab for treating inflammatory bowel disease (IBD) in these patients.
  • Researchers analyzed 16 studies involving 163 solid organ transplant recipients to assess outcomes related to infections, complications, and therapy discontinuation.
  • The study found infection rates of approximately 20.09 per 100 person-years, with serious infections at 17.39 per 100 person-years, but reported no deaths or significant issues related to the use of biologic therapies.
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Unlabelled: Since the authors are not responding to the editor’s requests to fulfill the editorial requirement, therefore, the article has been withdrawn. Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused. The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.

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Article Synopsis
  • This systematic review and meta-analysis assessed the effectiveness and safety of biologic therapies for patients with steroid-refractory microscopic colitis (MC).
  • A total of 376 studies were screened, resulting in 13 articles focused on 78 patients, showing remission rates of approximately 66% at 3-6 weeks and 54% at 12-16 weeks, with a 100% clinical response rate initially but a drop to around 67% later on.
  • The study found a significant incidence of medication discontinuation (16.1%) as the most common adverse event, and concluded that while there is low-quality evidence supporting the short-term use of biologics, more rigorous research is needed to clarify their long-term efficacy
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Quality measures were established to develop standards to help assess quality of care, yet variation in endoscopy exists. We performed a systematic review to assess the overall quality of evidence cited in formulating quality measures in endoscopy. A systematic search was performed on multiple databases from inception until November 15, 2020, to examine the quality measures proposed by all major societies.

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Background: Evidence regarding outcomes in inflammatory bowel disease (IBD) hospitalizations with coexisting cirrhosis is scant. We queried the National Inpatient Sample (NIS) database to evaluate the impact of cirrhosis on hospitalization characteristics and outcomes in patients with Crohn's disease and ulcerative colitis.

Methods: All admissions that listed IBD as a primary diagnosis by ICD-10-CM code (K50.

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Background: The objective of our systematic review and meta-analysis was to evaluate the effectiveness and safety of tofacitinib in the treatment of moderate-severe ulcerative colitis (UC).

Methods: We searched Medline, Embase, Web of Science, and Cochrane Central to identify articles and abstracts reporting efficacy or safety data on tofacitinib use in UC. Primary outcome assessed was remission.

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Background: Patients' perception regarding the risks of COVID-19 infection with gastrointestinal (GI) and the preventive measures taken in GI endoscopy units to mitigate infection risk remains unclear. We aimed to assess patients' perception regarding risks of COVID-19 with GI endoscopy and the changes in the endoscopy unit as a result of the ongoing pandemic.

Methods: Outpatients undergoing GI endoscopy at our institution were categorized into those scheduled to undergo GI endoscopy (preprocedure) and those who had recently undergone GI endoscopy during the pandemic (postprocedure).

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Rationale: Adult hyperammonemia is most often the result of hepatic dysfunction. Hyperammonemia in the setting of normal hepatic function is a much less common phenomenon and has usually been associated with medications and certain disease states. Here, we present an unusual case of severe hyperammonemia caused physiologically by intense muscle activity in a patient lacking any evidence of liver disease.

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Skeletal coccidioidomycosis is extremely rare and in the non-endemic areas, diagnosis is often delayed or missed resulting in extensive and unnecessary medical investigation for other diseases. The authors report a case of disseminated skeletal coccidioidomycosis in a previously healthy person living in a non-endemic area, who was initially thought to have a malignancy. Due to the presence of multiple expansile lytic bone lesions on x-rays and CT scan, an extensive investigation for malignancy was done.

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Voriconazole is a newer systemic antifungal agent effective against Candida and Aspergillus. There are few reports of its safe use in newborns. We report the first case series of safe Voriconazole use in critically ill newborns with cardiac disease along with several other cardiac drugs without any significant drug interaction or side-effect.

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Objectives: This paper attempts to validate the programme of structured play lasting 90 minutes a day, for use in orphanages, to check if it can be replicated in other orphanages, with similar results.

Methods: A 2-week workshop on the structured play scheme was conducted at the Missionaries of Charity Orphanage in Delhi, the venue of the original project. 15 MOC sisters from 6 centers attended the workshop.

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Poisoning is one of the commonest pediatric emergencies. Most of poisonings in children below 5 years of age, are accidental and fortunately trivial, related to their exploratory nature. However a poisoned child may present as an acute emergency with or without multisystem involvement.

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Objective: To assess the usefulness of clinical risk index of babies (CRIB score) in predicting neonatal mortality in extremely preterm neonates, compared to birth weight and gestation.

Methods: 97 preterm neonates with gestational age less than 31 weeks or birth weight less than or equal to 1500 g were enrolled for the prospective longitudinal study. Relevant neonatal data was recorded.

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