Publications by authors named "Vijayalakshmi Rajasekaran"

Objective: In mesial temporal lobe epilepsy (MTLE), the ideal surgical approach to achieve seizure freedom and minimize morbidity is an unsolved question. Selective approaches to mesial temporal structures often result in suboptimal seizure outcomes. The authors report the results of a pilot study intended to evaluate the clinical feasibility of using an endoscopic anterior transmaxillary (eATM) approach for minimally invasive management of MTLEs.

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Article Synopsis
  • The study investigates the EEG findings in eight patients with COVID-19, focusing on neurologic issues like altered consciousness, which are common in severe cases of the disease.* -
  • Results showed that all patients had generalized background slowing, with some displaying epileptiform discharges, highlighting that patients with a history of epilepsy may be particularly vulnerable.* -
  • The research emphasizes the correlation between COVID-19 and serious neurological symptoms, noting that five out of eight patients with abnormal EEG outcomes ultimately faced fatal results from the infection.*
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Background: Use of certain antiseizure drugs (ASDs) during pregnancy increases the risk of major congenital malformations, while less is known about newer ASDs. Based on the safety of levetiracetam, brivaracetam may be similarly safe in pregnancy; however, no cases have been published to date.

Aims Of The Study: We retrospectively identified three women with epilepsy treated with brivaracetam during pregnancy and described the maternal and neonatal outcomes.

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Objective: To compare the yield of epileptiform abnormalities on 30-minute recordings with those greater than 45 minutes.

Methods: We performed a prospective observational cross-sectional study of all outpatient routine EEGs comparing the rate of interictal epileptiform discharges (IEDs) and clinical events during the initial 30 minutes (routine) with those occurring in the remaining 30-60 minutes (extended). A relative increase of 10% was considered clinically significant.

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Objective: Reducing health and economic burdens from diagnostic delay of psychogenic nonepileptic seizures (PNES) requires prompt referral for video electroencephalography (VEEG) monitoring, the diagnostic gold standard. Practitioners make VEEG referrals when semiology suggests PNES, although few semiological signs are supported by well-designed studies, and most VEEG studies neglect to concurrently measure how accurately seizure witnesses can ascertain semiology. In this study, we estimate the value of eyewitness-reported and video-documented semiology for predicting PNES, and we measure accuracy of eyewitness reports.

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