Publications by authors named "Vijaya Sudhakara Rao Kola"

The endocrine control of food intake remains incompletely understood, and whether the leptin receptor (LepR)-mediated anorexigenic pathway in the hypothalamus is negatively regulated by a humoral factor is unknown. Here, we identify an appetite-stimulating factor - ASRA - that represents a peripheral signal of energy deficit and orthosterically antagonizes LepR signaling. encodes an 8 kD protein that is abundantly and selectively expressed in adipose tissue and to a lesser extent, in liver.

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Land plants have developed robust roots to grow in diverse soil ecosystems. The distal end of the root tip has a specialized organ called the 'root cap'. The root cap assists the roots in penetrating the ground, absorbing water and minerals, avoiding heavy metals and regulating the rhizosphere microbiota.

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In rice (Oryza sativa L.), during the course of domestication, numerous beneficial alleles remain untapped in the progenitor wild species and landraces. This study aims at uncovering these promising alleles of six key genes influencing the yield, such as DEP1, Ghd7, Gn1a, GS3, qSW5 and sd1 by targeted resequencing of the 200 rice genotypes.

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Article Synopsis
  • The yellow stem borer (YSB) is a major pest in rice farming, significantly impacting crop yields during its larval stage, which is crucial for understanding its biology and pest control strategies.
  • Transcriptome analysis at various larval stages revealed 24,775 transcripts associated with key processes such as metabolism, detoxification, and chemoreception, providing insights into larval development and adaptive mechanisms of YSB.
  • This research is the first to characterize the YSB transcriptome and pinpoint vital genes, paving the way for innovative pest control methods and potential advancements in developing resistant rice varieties using modern genetic techniques.
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RNAi is a powerful tool to target the insect genes involved in host-pest interactions. Key insect genes are the choice for silencing to achieve pest derived resistance where resistance genes are not available in gene pool of host plant. In this study, an attempt was made to determine the effect of dsRNA designed from two genes Cytochrome P450 derivative (CYP6) and Aminopeptidase N (APN) of rice yellow stem borer (YSB) on growth and development of insect.

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Article Synopsis
  • RNA interference (RNAi) is a gene silencing mechanism in plants and animals, utilizing small RNA molecules and proteins like Dicer and Argonaute to suppress key genes in pests.
  • Through RNAi, scientists can target specific genes in insects that are crucial for their survival, offering promising avenues for pest control in agriculture.
  • The text highlights the challenges of implementing RNAi in insect management, such as identifying effective targets and delivery methods, while also discussing strategies to overcome these hurdles.
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