Publications by authors named "Vijaya Sahadeo"
Aims: The present investigation is targeted towards the synthesis of a novel analogue of a natural peptide of marine origin.
Background: Marine sponges are enriched with bioactive secondary metabolites, especially circu-lar peptides. Heterocycles are established organic compounds with potential biological value.
Article Synopsis
- Peptides, such as cyclooligopeptides and depsipeptides from cyanobacteria, show promising characteristics for drug discovery due to their unique structural properties and diverse pharmacological activities.
- The study reviews the natural sources, chemical properties, and biological profiles of cyanobacteria-derived thiazoline-based polypeptides (CTBCs), emphasizing their role as potential drug targets and their advantages over traditional small molecules.
- CTBCs demonstrate enhanced stability and binding to targets, suggesting they could address unmet medical needs and serve as valuable compounds in the development of new therapeutics.